Diff Profiles › MTBLS4893_0003_00000003

Normal_vs_Neural_Tube_Defect

Normal vs Neural_Tube_Defect

p-value ≤ 0.05 1484 significant 2025-09-26 00:00:00 Study: MTBLS4893
1677 Total Features
1484 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS4893_0003_00000003
Linked study
MTBLS4893 — Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Feces metabolomics)
Comparison
Normal vs Neural_Tube_Defect
Group A
Control samples with normal condition.. Provides a reference point for identifying metabolic differences due to neural tube defects.
Group B
Experimental samples with neural tube defect condition.. Crucial for understanding the metabolic changes associated with neural tube defects.
Total features tested
1677
Significant features
1484
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
OIOMUGZSHNAEMH-UHFFFAOYSA-N 5-hydroxy-N-[(6-oxopiperidin-2-yl)methyl]-2-(2,2,2-triluoroethoxy)benzamide up 3.658e+09 6.35e-10
RXWVHRYZTWZATH-XSLAGTTESA-N Tetrahydropteroyltri-L-glutamate up 2.107e+10 4.09e-08
DSZBEWXQBVATQX-UHFFFAOYSA-N — up 5.593e+09 3.99e-08
FDYQQDJLOXIANP-BHVANESWSA-N — up 2.598e+09 5.99e-08
GXSGZLLXMDVQAS-UHFFFAOYSA-N 4-[3-methoxy-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]butan-2-one up 5.475e+09 4.65e-07
BBRNVDBLOTVLMB-VURMDHGXSA-N [(5Z)-8-hydroxy-6,10,10-trimethyl-2-methylidene-3,7-dioxo-4-bicyclo[7.2.0]undec-5-enyl] acetate down 6.353e-10 3.36e-07
KQBVSIZPUWODNU-UHFFFAOYSA-N 5,14-dihydroxy-3-[4-hydroxy-6-methyl-5-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-13-methyl-17-(5-oxo-2H-uran-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde up 3.359e+09 8.44e-07
UXIGZRQVLGFTOU-VQXQMPIVSA-N Ro 42-5892 up 3.514e+09 9.98e-07
AJLVEHFNMNRXNI-UHFFFAOYSA-N 2-(hydroxymethyl)-6-(2-hydroxypropoxy)oxane-3,4,5-triol up 3.385e+09 1.11e-06
BZQRJBLJDFPOBX-FOERLQQGSA-N 6-hydroxy-3-[(1E,3E,5E,7Z,9E,11E,13E,15Z)-18-(4-hydroxy-2,6,6-trimethyl-3-oxocyclohexen-1-yl)-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15-octaen-17-ynyl]-2,4,4-trimethylcyclohex-2-en-1-one up 5.596e+09 1.74e-06