Diff Profiles › MTBLS3750_0001_00000006

G1_PBS_vs_G2_DSS

PBS vs DSS

p-value ≤ 0.05 2064 significant 2025-09-26 00:00:00 Study: MTBLS3750
4548 Total Features
2064 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS3750_0001_00000006
Linked study
MTBLS3750 — Diallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice
Comparison
PBS vs DSS
Group A
Vehicle control group treated with PBS.. Provides baseline for evaluating the effects of other treatments.
Group B
Group treated with DSS to induce intestinal infection.. Models the disease state for comparison with treatment effects.
Total features tested
4548
Significant features
2064
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
JHHZQADGLDKIPM-AATRIKPKSA-N (E)-hept-3-en-2-one up 3.793e+09 8.37e-11
LAWSLZINBLIPFW-NRPCDHBGSA-N methyl (E,7S)-7-acetyloxy-7-[(1R,2S)-4-chloro-2-hydroxy-2-[(Z)-oct-2-enyl]-5-oxocyclopent-3-en-1-yl]hept-5-enoate up 8.054e+09 9e-07
FJLGEFLZQAZZCD-JUFISIKESA-N <em>rac</em>-(3<i>R</i>,5<i>S</i>,6<i>E</i>)-7-(3-(4-fluorophenyl)-1-(1-methylethyl)-1<em>H</em>-indol-2-yl)-3,5-dihydroxy-6-heptenoic acid up 1.192e+10 1.23e-06
LJTKAUAKTFMWRP-UHFFFAOYSA-N 1-ethyl-6-luoro-7-(4-methylpiperazin-1-yl)-1-oxido-4-oxoquinolin-1-ium-3-carboxylic acid up 2.115e+09 5.74e-07
KXMANOZDITZERP-PABFRNLHSA-N (E,9S)-11-(2-ethyl-3-oxocyclopenten-1-yl)-9-hydroxyundec-10-enoic acid up 6.646e+09 1.1e-05
KSBALECVCJXYHU-IBGZPJMESA-N (2S)-5,7-Dihydroxy-6-(2-hydroxybenzyl)-2-phenyl-2,3-dihydro-4H-chromen-4-one up 2.816e+09 1.22e-05
LIBLKFXXSFBDCF-RZTQZAHISA-N [(2R)-1-[[(2S)-2,3-dihydroxypropoxy]-hydroxyphosphoryl]oxy-3-hexadecoxypropan-2-yl] (9Z,12Z)-heptadeca-9,12-dienoate up 3.483e+10 3.98e-05
UERLHGISINMPNT-ADWHDFFQSA-N [(2R)-1-[[(2S)-2,3-dihydroxypropoxy]-hydroxyphosphoryl]oxy-3-[(Z)-hexadec-1-enoxy]propan-2-yl] (Z)-tetradec-9-enoate up 2.548e+09 1.3e-05
NCFTXMQPRQZFMZ-WERGMSTESA-M Cefoperazone sodium up 4.063e+09 0.000209
ZXTZNOMUNZDWOM-SVTFAFHISA-N [(2R)-1-[[[(2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-3-[(9Z,12Z,15Z)-octadeca-9,12,15-trienoyl]oxypropan-2-yl] (9Z,12Z)-octadeca-9,12-dienoate down 8.746e-10 0.000129