Diff Profiles › MTBLS3750_0002_00000006

G1_PBS_vs_G2_DSS

PBS vs DSS

p-value ≤ 0.05 1576 significant 2025-09-26 00:00:00 Study: MTBLS3750
3411 Total Features
1576 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS3750_0002_00000006
Linked study
MTBLS3750 — Diallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice
Comparison
PBS vs DSS
Group A
Vehicle control group treated with PBS.. Provides baseline for evaluating the effects of other treatments.
Group B
Group treated with DSS to induce intestinal infection.. Models the disease state for comparison with treatment effects.
Total features tested
3411
Significant features
1576
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
ARBHCEGTLUXZRX-YNRRLODASA-N 7-hydroxy-6-methylhepta-3,5-dienal up 1.082e+09 1.01e-10
BMAXIMHASVHMKO-NVPSEEHGSA-N [(2R)-1-octadecoxy-3-phosphonooxypropan-2-yl] (6Z,9Z,12Z)-octadeca-6,9,12-trienoate up 2.786e+09 3.49e-08
UFBCBSNKWKPSRJ-SNPVRQPZSA-N (5Z,8Z,11Z,14Z)-N-butylicosa-5,8,11,14-tetraenamide down 0.0004017 6.53e-10
RKIDALSACBQVTN-HHHXNRCGSA-N POVPC up 1.399e+09 0.000417
LVBVWNJPMXCQJE-CBBDEUQJSA-N Mesaconyl-C1-CoA down 6.332e-11 0.00152
KQBVSIZPUWODNU-UHFFFAOYSA-N 5,14-dihydroxy-3-[4-hydroxy-6-methyl-5-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-13-methyl-17-(5-oxo-2H-uran-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde up 1.743e+09 0.000791
LMDZBCPBFSXMTL-UHFFFAOYSA-N — down 4.951e-10 0.000895
JQFZHHSQMKZLRU-IUCAKERBSA-N arginyllysine up 2.092e+05 5.31e-06
JWSLONXEOIUDBS-RUNYOZRHSA-N (2S)-2-amino-3-[[(2R)-2-[(E)-5,8-dioxooct-6-enoyl]oxy-3-[(Z)-octadec-9-enoyl]oxypropoxy]-hydroxyphosphoryl]oxypropanoic acid down 4.333e-10 0.00158
QHKABHOOEWYVLI-UHFFFAOYSA-N 2-Ketovaline down 1.364e-09 0.00116