Diff Profiles › MTBLS2840_0002_00000026

Calu3_Mock_DMEM_vs_Calu3_10uM_NIC

Calu3_Mock_DMEM vs Calu3_10uM_NIC

p-value ≤ 0.05 36 significant 2025-09-26 00:00:00 Study: MTBLS2840
47 Total Features
36 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS2840_0002_00000026
Linked study
MTBLS2840 — SARS-CoV-2-reprogrammed metabolism and autophagy reduction uncover host-targeting antivirals
Comparison
Calu3_Mock_DMEM vs Calu3_10uM_NIC
Group A
Calu-3 cells treated with DMEM as mock control for SARS-CoV-2.. Provides baseline data for evaluating the effects of treatments on Calu-3 cells.
Group B
Calu-3 cells treated with 10 µM Niclosamide.. Evaluates the effect of Niclosamide on SARS-CoV-2 propagation in Calu-3 cells.
Total features tested
47
Significant features
36
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
DCXYFEDJOCDNAF-REOHCLBHSA-N (2<i>S</i>)-2-ammonio-3-carbamoylpropanoate down 0.1544 1.48e-06
MEFKEPWMEQBLKI-AIRLBKTGSA-N AdoMet down 0.1382 3.51e-05
OIRDTQYFTABQOQ-KQYNXXCUSA-N Adenosin down 0.1273 7.71e-05
MTCFGRXMJLQNBG-REOHCLBHSA-N <small>L</small>-serine zwitterion down 0.3079 6.18e-07
WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-Glucose down 0.1241 0.00111
ATHGHQPFGPMSJY-UHFFFAOYSA-N N-(3-Aminopropyl)-1,4-butane-diamine down 0.1353 0.0015
MQTAVJHICJWXBR-UHFFFAOYSA-N 1-<em>N</em>-acetylspermidine down 0.2184 0.000203
KIDHWZJUCRJVML-UHFFFAOYSA-N Butane-1,4-diamine down 0.2026 0.000302
HNDVDQJCIGZPNO-YFKPBYRVSA-N (2<i>S</i>)-2-ammonio-3-(1<em>H</em>-imidazol-4-yl)propanoate down 0.3881 8.29e-06
WUUGFSXJNOTRMR-IOSLPCCCSA-N 5'-Deoxy-5'-(methylthio)adenosine down 0.1294 0.00467