Diff Profiles › MTBLS2840_0001_00000026

Calu3_Mock_DMEM_vs_Calu3_10uM_NIC

Calu3_Mock_DMEM vs Calu3_10uM_NIC

p-value ≤ 0.05 44 significant 2025-09-26 00:00:00 Study: MTBLS2840
44 Total Features
44 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS2840_0001_00000026
Linked study
MTBLS2840 — SARS-CoV-2-reprogrammed metabolism and autophagy reduction uncover host-targeting antivirals
Comparison
Calu3_Mock_DMEM vs Calu3_10uM_NIC
Group A
Calu-3 cells treated with DMEM as mock control for SARS-CoV-2.. Provides baseline data for evaluating the effects of treatments on Calu-3 cells.
Group B
Calu-3 cells treated with 10 µM Niclosamide.. Evaluates the effect of Niclosamide on SARS-CoV-2 propagation in Calu-3 cells.
Total features tested
44
Significant features
44
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
JDTUMPKOJBQPKX-GBNDHIKLSA-N D-Sedoheptulose 7-phosphate down 0.1829 8.45e-09
XTWYTFMLZFPYCI-KQYNXXCUSA-N 5'-adenylphosphoric acid down 0.1823 1.08e-06
ZWIADYZPOWUWEW-XVFCMESISA-N Cytidine, 5'-(trihydrogen pyrophosphate) down 0.171 3.71e-06
PCDQPRRSZKQHHS-XVFCMESISA-N 5'-CTP down 0.1148 4.05e-05
RGWHQCVHVJXOKC-SHYZEUOFSA-N dCTP down 0.1406 1.72e-05
XKMLYUALXHKNFT-UUOKFMHZSA-N GUANOSINE-5'-TRIPHOSPHATE down 0.1369 2.84e-05
LFTYTUAZOPRMMI-CFRASDGPSA-N (2R,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name) down 0.1792 7.41e-06
ZKHQWZAMYRWXGA-KQYNXXCUSA-N Adenosine 5'-triphosphate down 0.1233 6.8e-05
DTBNBXWJWCWCIK-UHFFFAOYSA-N PEP down 0.0527 0.00138
ZKLLSNQJRLJIGT-UYFOZJQFSA-N D-Fructose 1-phosphate down 0.1284 9.27e-05