Metabolite details
Reactome pathways
- R-HSA-1430728 - Metabolism
- R-HSA-1643685 - Disease
- R-HSA-352230 - Amino acid transport across the plasma membrane
- R-HSA-379716 - Cytosolic tRNA aminoacylation
- R-HSA-379724 - tRNA Aminoacylation
- R-HSA-379726 - Mitochondrial tRNA aminoacylation
- R-HSA-382551 - Transport of small molecules
- R-HSA-392499 - Metabolism of proteins
- R-HSA-425407 - SLC-mediated transmembrane transport
- R-HSA-427975 - Proton/oligopeptide cotransporters
- R-HSA-442660 - SLC-mediated transport of neurotransmitters
- R-HSA-5223345 - Miscellaneous transport and binding events
- R-HSA-5619094 - Variant SLC6A14 may confer susceptibility towards obesity
- R-HSA-5619102 - SLC transporter disorders
- R-HSA-5619115 - Disorders of transmembrane transporters
- R-HSA-70921 - Histidine catabolism
- R-HSA-71240 - Tryptophan catabolism
- R-HSA-71291 - Metabolism of amino acids and derivatives
- R-HSA-72766 - Translation
- R-HSA-9958863 - SLC-mediated transport of amino acids
- R-HSA-9959399 - SLC-mediated transport of oligopeptides
Observed in studies
- Biological effect of chronic mistranslation in mammalian cells
- Untargeted metabolomics to understand the basis of phenotypic differences in amphotericin B-resistant Leishmania parasites
- Resveratrol metabolism in HepG2 (human hepatocytes), HaCaT (human keratinocytes), and C2C12 (mouse myoblasts)
- Effect of L-carnitine administration on lipid and metabolite content in sheep infraspinatus muscle after tendon release
- Jejunal inflammatory cytokines, barrier proteins and microbiome-metabolome responses to early supplementary feeding of Bamei suckling piglets
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Escherichia coli assays)
- The response of Chlamydomonas reinhardtii to nitrogen deprivation: a systems biology analysis
- Metabolic Dynamics of In Vitro CD8+ T Cell Activation.
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Streptococcus pneumoniae assays)
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Streptococcus pyogenes assays)
- Multi-Omics Analysis Reveals Disturbance of Nanosecond Pulsed Electric Field in the Serum Metabolic Spectrum and Gut Microbiota
- Transcriptional differentiation of Trypanosoma brucei during in vitro acquisition of resistance to acoziborole
- Metabolic Dynamics in <i>Escherichia coli</i>-Based Cell-Free Systems
- Integrated Analyses of the Gut Microbiota, Intestinal Permeability and Serum Metabolome Phenotype in Rats with Alcohol Withdrawal Syndrome
- Efficacy of Zhuyu Pill Intervention in a Cholestasis Rat Model: Mutual Effects on Fecal Metabolism and Microbial Diversity
- Fat Deposition in the Muscle of Female and Male Yak and the Correlation of Yak Meat Quality with Fat
- Red-Fleshed Apple Anthocyanin Extracts Attenuate Male Reproductive System Dysfunction Caused by Busulfan in Mice (Mouse blood plasma; UPLC-MS/MS assays)
- Transcriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth
- SARS-CoV-2-reprogrammed metabolism and autophagy reduction uncover host-targeting antivirals
- Changes and correlations of intestinal flora and liver metabolite profiles in mice with gallstones
- Multiomics of tomato glandular trichomes reveals distinct features of central carbon metabolism supporting high productivity of specialized metabolites
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 21)
- High complexity and diel dynamics of planktonic microbiome revealed by multi-omics in Taihu, China
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 10)
- Multiple biochemical indices and metabolomics of Clonorchis sinensis provide a novel interpretation of biomarkers
- Analysis of Growth Phases of Enterotoxigenic Escherichia coli Reveals a Distinct Transition Phase before Entry into Early Stationary Phase with Shifts in Tryptophan, Fucose, and Putrescine Metabolism and Degradation of Neurotransmitter Precursors
- Distinct succinate modifying products are clinically diagnostic and prognostic biomarkers for fumarate hydratase deficient renal cell carcinoma
- Gut microbiome drives individual memory variation in bumblebees
- The Manchurian Walnut Genome: Insights into Juglone and Lipid Biosynthesis.
- Mechanical force promotes dimethylarginine dimethylaminohydrolase 1-mediated hydrolysis of the metabolite asymmetric dimethylarginine to enhance bone formation
- Diallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice
- Appropriate taxonomic classification of intestinal microbiome by 16S rRNA gene targeting metagenomic approach
- Metabolism Disorder Promotes Isoproterenol-induced Myocardial Injury in Mice with High Temperature and High Humidity and High-Fat Diet
- Exercise-generated β-aminoisobutyric acid (BAIBA) reduces cardiomyocytes metabolic stress and apoptosis caused by mitochondrial dysfunction through the miR-208b/AMPK pathway
- Metabolic profilings of rat INS-1 β-cells under changing levels of essential amino acids
- Characterization of white tea metabolome: comparison against green and black tea by a nontargeted metabolomics approach.
- Transcriptome and Metabolome Analyses Reveal Differences in Terpenoid and Flavonoid Biosynthesis in Cryptomeria fortunei Needles Across Different Seasons
- Effects of Radiofrequency Field from 5G Communications on fecal microbiome and metabolome profiles in mice
- Novel Potential Diagnostic Serum Biomarkers of Metabolomics in Osteoarticular Tuberculosis Patients: A Preliminary Study
- Homeostasis of the biosynthetic E. coli metabolome
- Comparative Metabolomic Profiling of Compatible and Incompatible Interactions Between Potato and Phytophthora infestans
- Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors
- Integrated Metabolomics and Transcriptomics Analyses Reveal Anthocyanin and Carotenoid Biosynthesis Involved in Color Development in Willow Bark
- Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Feces metabolomics)
- Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Brain tissue metabolomics)
- Interaction between Cervical Microbiota and Host Gene Regulation in Caesarean Section Scar Diverticulum
- Mechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis
- DT-109 ameliorates nonalcoholic steatohepatitis in nonhuman primates
- Multiomic analysis revealed the potential role of rumen microbes in heat stress
- Effect of heat stress on serum enzyme activity, antioxidant capacity and immune parameter metabolomics datasets in Holstein cows at different growth stages
- Stage-specific roles of microbial dysbiosis and metabolic disorders in rheumatoid arthritis
- Alterations in the gut microbiota and metabolomics of seafarers after a six-month sea voyage
- Bile acid is a significant host factor shaping the gut microbiome of diet induced obese mice (untargeted metabolome profile assay)
- Metabolic disorder and intestinal microflora dysbiosis in chronic inflammatory demyelinating polyradiculoneuropathy
- 4-Octyl itaconate as a metabolite derivative inhibits inflammation via alkylation of STING
- FSCN1 as a new druggable target in adrenocortical carcinoma
- Transcriptomics and metabolomics analysis reveal the anti-oxidation and immune boosting effects of mulberry leaves in growing mutton sheep
- Extracellular-acidosis restricts one-carbon metabolism and preserves T cell stemness
- TGF-β uncouples glycolysis and inflammation in macrophages and controls the survival during sepsis
- Genetic mapping and molecular mechanism behind color variation in the Asian vine snake
- Metabolic consequences of cobalamin scarcity in diatoms as revealed through metabolomics (Thalassiosira pseudonana study)
- Metabolic consequences of cobalamin scarcity in diatoms as revealed through metabolomics (Navicula pelliculosa study)
- Disturbed Microbiota-Metabolites-Immune Interaction Network is Associated with Olfactory Dysfunction in Patients with Chronic Rhinosinusitis
- L-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS positive mode)
- L-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS negative mode)
- Plasma metabolite changes in dairy cows during parturition identified using untargeted metabolomics.
- Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites (Blood fraction)
- Searching for Drug Synergy Against Cancer Through Polyamine Metabolism Impairment: Insight Into the Metabolic Effect of Indomethacin on Lung Cancer Cells.
- Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites (Blood plasma and RBC fractions)
- Changing environments and genetic variation: inbreeding does not compromise short-term physiological responses
Observed in differential profiles
- rps2_wildtype_vs_rps2_A226Y
- G1_Wild_Type_vs_G2_AmBRAcl1
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- Control_16.6_months_vs_Treatment_16.6_months
- Supplementary_feeding_vs_Control
- RPMI_B36_vs_Pooled_Sera_B36
- 0h_vs_24h
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- G1_Pooled_Sera_Blood_4559_vs_G2_RPMI_Glucose_Blood_4559
- G1_RPMI_modified_Blood_M1T1_5448_vs_G2_Pooled_sera_Blood_M1T1_5448
- Control_vs_nsPEF_7_day
- WT_vs_WT_Aco
- G1_Exp1_0_hours_vs_G2_Exp1_6_hours
- Alcohol_Treatment_vs_Control
- Control_vs_CF_high
- Male_vs_Female
- Control_vs_Busulfan_5_mg_kg_RAAE
- Wild_Type_vs_YQ2-gal
- Calu3_Mock_DMEM_vs_Calu3_10uM_NIC
- Control_vs_Lithogenic_Diet
- Solanum_habrochaites_leaf_vs_glandular_trichome
- Sham_vs_UIR
- 2:00 AM_Membrane_vs_2:00 AM_Net
- Sham_vs_UIR
- Control_14dpi_vs_Infected_14dpi
- Control_14dpi_vs_Infected_14dpi
- E1777_Intracellular_MidLog_vs_E1777_Intracellular_EarlyStationary
- Normal_control_no_tumor_vs_FH_deficient_RCC
- Hindgut_Control_vs_Lactobacillus_apis
- Embryo_S1_vs_Embryo_S4
- Control_vs_Exercise
- G1_PBS_vs_G2_DSS
- Untreated_vs_Antibiotic_Treated
- Untreated_vs_Antibiotic_Treated
- Control_vs_Isoproterenol
- Sham_vs_Heart_Failure_Sedentary
- Sham_vs_Heart_Failure_Sedentary
- G1_Control_vs_G2_Arginine_Addition
- White_Tea_0h_vs_White_Tea_36h
- Summer_vs_Winter
- Sham_vs_Radiofrequency
- Healthy_Control_vs_Osteoarticular_Tuberculosis
- Glu_BW25113_vs_Pyr_BW25113
- Ziyun_No.1_0h_vs_Ziyun_No.1_96h
- Wild_Type_vs_Gene_Knockout
- Purple_vs_Green
- Normal_vs_Neural_Tube_Defect
- Normal_vs_Neural_Tube_Defect
- Normal_vs_Neural_Tube_Defect
- Control_vs_CSD
- Control_vs_ZYP_High_Dose
- Control_Liver_vs_Treatment_Liver
- Dc-N_vs_Dc-HS
- Dcs_N_vs_Dcs_HS
- Healthy_vs_RAS4
- Control_0d_vs_Treatment_180d
- Normal_Diet_vs_High-fat_Diet
- Normal_Diet_vs_High-fat_Diet
- Normal_Diet_vs_High-fat_Diet
- CIDP_patient_vs_healthy_control
- CIDP_patient_vs_healthy_control
- Control_vs_DMXAA16h
- Control_Vehicle_vs_FSCN1_Knockout_Vehicle
- Control_vs_Fermented_Mulberry_Leaves
- Control_vs_Lactic_Acid
- Control_vs_TGF-beta_Treatment
- Yellow_Skin_vs_Green_Skin
- Saturating_Limiting_vs_Saturating_Replete
- Navicula_pelliculosa_Saturating_Limiting_vs_Saturating_Replete
- Normal_vs_Abnormal
- Normal_vs_Abnormal
- SAR-S_vs_SAR-R
- SAR-R_vs_SAR-S
- After_Calving_vs_21_Days_Before_Due_Date
- A549_0uM_vs_A549_1uM
- Human_Blood_vs_Human_Plasma
- Human_Blood_vs_Human_Plasma
- Inbreeding_Growth_Chamber_0_day_vs_Inbreeding_Growth_Chamber_92_day
- Blood_vs_Plasma