Diff Profiles › MTBLS1167_0002_00000001

G1_Wild_Type_vs_G2_AmBRAcl1

Wild_Type vs AmBRAcl1

p-value ≤ 0.05 6 significant 2025-09-26 00:00:00 Study: MTBLS1167
16 Total Features
6 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS1167_0002_00000001
Linked study
MTBLS1167 — Untargeted metabolomics to understand the basis of phenotypic differences in amphotericin B-resistant Leishmania parasites
Comparison
Wild_Type vs AmBRAcl1
Group A
Wild type Leishmania mexicana samples. Baseline group for comparison with resistant samples to understand resistance mechanisms.
Group B
AmB-resistant L. mexicana line AmBRAcl1. Helps in understanding the resistance mechanisms in AmBRAcl1 line.
Total features tested
16
Significant features
6
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
PHDOXVGRXXAYEB-VJANTYMQSA-N N1,N8-Bis(glutathionyl)spermidine down 0.05197 4.57e-05
QIVBCDIJIAJPQS-VIFPVBQESA-N (2<i>S</i>)-2-ammonio-3-(1<em>H</em>-indol-3-yl)propanoate down 0.3688 5.48e-06
RWSXRVCMGQZWBV-WDSKDSINSA-N 5-L-Glutamyl-L-cysteinylglycine down 0.4095 0.00128
ODKSFYDXXFIFQN-BYPYZUCNSA-N (2<i>S</i>)-2-amino-5-guanidinopentanoic acid up 1.719 0.000923
AHLPHDHHMVZTML-BYPYZUCNSA-N (<i>S</i>)-α,δ-diaminovaleric acid up 1.766 0.00213
ONIBWKKTOPOVIA-BYPYZUCNSA-N (2S)-pyrrolidinium-2-carboxylate up 1.55 0.0114