trypanothione

Metabolite details

Identifier

PHDOXVGRXXAYEB-VJANTYMQSA-N

InChI Key

PHDOXVGRXXAYEB-VJANTYMQSA-N

IUPAC name

(2S,7R,26R,31S)-2,31-diamino-5,8,11,22,25,28-hexaoxo-7,26-bis(sulfanylmethyl)-6,9,12,16,21,24,27-heptaazadotriacontane-1,32-dioic acid

Preferred name

trypanothione

INN name

—

Synonym

N1,N8-Bis(glutathionyl)spermidine

ChEBI

CHEBI:17842

Reactome pathways

• No Reactome pathways listed for this metabolite.

Observed in studies

• Untargeted metabolomics to understand the basis of phenotypic differences in amphotericin B-resistant Leishmania parasites
• Transcriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth
• Diallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice
• Mining for natural product antileishmanials in a fungal extract library

Observed in differential profiles

• G1_Wild_Type_vs_G2_AmBRAcl1
• Wild_Type_vs_YQ2-gal
• G1_PBS_vs_G2_DSS
• Untreated_vs_HD871-1_treatment
• Untreated_vs_HD871-1_treatment