Diff Profiles › MTBLS868_0002_00000004

Untreated_vs_HD871-1_treatment

Untreated vs HD871-1_treatment

p-value ≤ 0.05 12 significant 2025-09-26 00:00:00 Study: MTBLS868
12 Total Features
12 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS868_0002_00000004
Linked study
MTBLS868 — Mining for natural product antileishmanials in a fungal extract library
Comparison
Untreated vs HD871-1_treatment
Group A
Untreated samples with dimethyl sulfoxide. Serves as the baseline for treatment comparisons
Group B
Samples treated with HD871-1. Evaluates the effect of HD871-1 treatment on Leishmania mexicana
Total features tested
12
Significant features
12
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
LEVWYRKDKASIDU-IMJSIDKUSA-N (2<i>R</i>,2'<i>R</i>)-3,3'-dithiobis(2-ammoniopropanoate) up 1e+06 0.00115
UFIVEPVSAGBUSI-REOHCLBHSA-N L-Dihydroorotic acid down 0.06345 0.00554
KHWCHTKSEGGWEX-RRKCRQDMSA-N 2'-deoxyadenosine monophosphate up 3.199 2.12e-05
PHDOXVGRXXAYEB-VJANTYMQSA-N N1,N8-Bis(glutathionyl)spermidine down 0.2101 0.000332
PXQPEWDEAKTCGB-UHFFFAOYSA-N OROTIC ACID down 0.1304 0.00457
GYOZYWVXFNDGLU-XLPZGREQSA-N Thymidylic acid up 3.996 0.000464
LTFMZDNNPPEQNG-KVQBGUIXSA-N 2'-deoxyguanosine 5'-monophosphate up 4.6 0.00103
UJLXYODCHAELLY-XLPZGREQSA-N thymidine 5'-diphosphate down 0.3746 2.91e-05
RWSXRVCMGQZWBV-WDSKDSINSA-N 5-L-Glutamyl-L-cysteinylglycine down 0.3659 0.000101
NCMVOABPESMRCP-SHYZEUOFSA-N Deoxycytidylate up 3.074 0.000967