Metabolite details
Reactome pathways
- R-HSA-1430728 - Metabolism
- R-HSA-1643685 - Disease
- R-HSA-209776 - Metabolism of amine-derived hormones
- R-HSA-209931 - Serotonin and melatonin biosynthesis
- R-HSA-352230 - Amino acid transport across the plasma membrane
- R-HSA-379716 - Cytosolic tRNA aminoacylation
- R-HSA-379724 - tRNA Aminoacylation
- R-HSA-379726 - Mitochondrial tRNA aminoacylation
- R-HSA-382551 - Transport of small molecules
- R-HSA-392499 - Metabolism of proteins
- R-HSA-425407 - SLC-mediated transmembrane transport
- R-HSA-442660 - SLC-mediated transport of neurotransmitters
- R-HSA-5619044 - Defective SLC6A19 causes Hartnup disorder (HND)
- R-HSA-5619094 - Variant SLC6A14 may confer susceptibility towards obesity
- R-HSA-5619102 - SLC transporter disorders
- R-HSA-5619115 - Disorders of transmembrane transporters
- R-HSA-5659735 - Defective SLC6A19 causes Hartnup disorder (HND)
- R-HSA-71240 - Tryptophan catabolism
- R-HSA-71291 - Metabolism of amino acids and derivatives
- R-HSA-72766 - Translation
- R-HSA-9958863 - SLC-mediated transport of amino acids
Observed in studies
- Biological effect of chronic mistranslation in mammalian cells
- Untargeted metabolomics to understand the basis of phenotypic differences in amphotericin B-resistant Leishmania parasites
- Absence of tmRNA Increases the Persistence to Cefotaxime and the Intercellular Accumulation of Metabolite GlcNAc in <i>Aeromonas veronii</i>.
- Absence of tmRNA increases the persistence to cefotaxime by upregulating the metabolites GlcNAc in Aeromonas veronii
- Cell-based and multi-omics profiling reveal dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei
- Hfq Regulates Efflux Pump Expression and Purine Metabolic Pathway to Increase the Trimethoprim Resistance in Aeromonas veronii
- A metabolite roadmap of the wood-forming tissue in Populus tremula (GC-MS assay; Wood ring and extraxylary tissue)
- Metabolic cooperation and spatiotemporal niche partitioning in a kefir microbial community; Interaction between the kefir isolates Lactococcus lactis and Acetobacter fabarum (GC-MS)
- Insights into Metabolic Changes Caused by the <i>Trichoderma virens</i>-Maize Root Interaction.
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Escherichia coli assays)
- Metabolic Dynamics of In Vitro CD8+ T Cell Activation.
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Klebsiella pneumoniae assays)
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Streptococcus pneumoniae assays)
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Streptococcus pyogenes assays)
- Multi-Omics Analysis Reveals Disturbance of Nanosecond Pulsed Electric Field in the Serum Metabolic Spectrum and Gut Microbiota
- Transcriptional differentiation of Trypanosoma brucei during in vitro acquisition of resistance to acoziborole
- Efficacy of Zhuyu Pill Intervention in a Cholestasis Rat Model: Mutual Effects on Fecal Metabolism and Microbial Diversity
- Fat Deposition in the Muscle of Female and Male Yak and the Correlation of Yak Meat Quality with Fat
- Red-Fleshed Apple Anthocyanin Extracts Attenuate Male Reproductive System Dysfunction Caused by Busulfan in Mice (Mouse blood plasma; UPLC-MS/MS assays)
- Metabolic characterization of the natural progression of chronic hepatitis B (Biogenic amine and Acyl-carnitine assays).
- Transcriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth
- Metabolic Responses of a Model Green Microalga Euglena gracilis to Different Environmental Stresses
- Metabolites from surface seawater collected in Narragansett Bay
- Changes and correlations of intestinal flora and liver metabolite profiles in mice with gallstones
- A Phosphate starvation response gene (psr1-like) is present in Micromonas pusilla and other marine algae and coordinates the metabolic response to phosphate deficiency
- Multiomics of tomato glandular trichomes reveals distinct features of central carbon metabolism supporting high productivity of specialized metabolites
- Distinct metabolic profiling is correlated with bisexual flowers formation resulting from exogenous ethephon induction in melon (<i>Cucumis melo</i> L.)
- High complexity and diel dynamics of planktonic microbiome revealed by multi-omics in Taihu, China
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 10)
- Multiple biochemical indices and metabolomics of Clonorchis sinensis provide a novel interpretation of biomarkers
- Analysis of Growth Phases of Enterotoxigenic Escherichia coli Reveals a Distinct Transition Phase before Entry into Early Stationary Phase with Shifts in Tryptophan, Fucose, and Putrescine Metabolism and Degradation of Neurotransmitter Precursors
- Distinct succinate modifying products are clinically diagnostic and prognostic biomarkers for fumarate hydratase deficient renal cell carcinoma
- Gut microbiome drives individual memory variation in bumblebees
- The Manchurian Walnut Genome: Insights into Juglone and Lipid Biosynthesis.
- Mechanical force promotes dimethylarginine dimethylaminohydrolase 1-mediated hydrolysis of the metabolite asymmetric dimethylarginine to enhance bone formation
- Metabolism Disorder Promotes Isoproterenol-induced Myocardial Injury in Mice with High Temperature and High Humidity and High-Fat Diet
- A Combined Proteomic and Metabolomic Strategy for Allergens Characterization in Natural and Fermented <em>Brassica napus</em> Bee Pollen
- Metabolic profilings of rat INS-1 β-cells under changing levels of essential amino acids
- Characterization of white tea metabolome: comparison against green and black tea by a nontargeted metabolomics approach.
- Transcriptome and Metabolome Analyses Reveal Differences in Terpenoid and Flavonoid Biosynthesis in Cryptomeria fortunei Needles Across Different Seasons
- Novel Potential Diagnostic Serum Biomarkers of Metabolomics in Osteoarticular Tuberculosis Patients: A Preliminary Study
- Homeostasis of the biosynthetic E. coli metabolome
- Comparative Metabolomic Profiling of Compatible and Incompatible Interactions Between Potato and Phytophthora infestans
- Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors
- Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Feces metabolomics)
- Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Brain tissue metabolomics)
- Sodium Butyrate mediates Histone Crotonylation and Alleviated Neonatal Rats Hypoxic-Ischemic Brain Injury Through Gut-Brain Axis (untargeted fecal metabolomics)
- Interaction between Cervical Microbiota and Host Gene Regulation in Caesarean Section Scar Diverticulum
- Mechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis
- Multiomic analysis revealed the potential role of rumen microbes in heat stress
- Effect of heat stress on serum enzyme activity, antioxidant capacity and immune parameter metabolomics datasets in Holstein cows at different growth stages
- Stage-specific roles of microbial dysbiosis and metabolic disorders in rheumatoid arthritis
- A Multi-Omics Analysis of Glycine max Leaves Reveals Alteration in Flavonoid and Isoflavonoid Metabolism Upon Ethylene and Abscisic Acid Treatment.
- Alterations in the gut microbiota and metabolomics of seafarers after a six-month sea voyage
- Bile acid is a significant host factor shaping the gut microbiome of diet induced obese mice (untargeted metabolome profile assay)
- Metabolic disorder and intestinal microflora dysbiosis in chronic inflammatory demyelinating polyradiculoneuropathy
- Transcriptomic and lipidomic profiling of subcutaneous and visceral adipose tissues in 15 vertebrates
- DNA-PKcs drives CKD progression by activating TAF7/RAPTOR/mTORC1 signaling-mediated metabolic reprogramming
- GABA regulates IL-1β production in macrophages
- Transcriptomics and metabolomics analysis reveal the anti-oxidation and immune boosting effects of mulberry leaves in growing mutton sheep
- Comparative metabolomic analysis of exudates of microcystin-producing and microcystin-free Microcystis aeruginosa strains
- Regulatory actors and alternative routes for Arabidopsis seed germination are revealed using a pathway‐based analysis of transcriptomic datasets
- TGF-β uncouples glycolysis and inflammation in macrophages and controls the survival during sepsis
- Unraveling the metabolic effects of benzophenone-3 on the endosymbiotic dinoflagellate Cladocopium goreaui
- Metabolic consequences of cobalamin scarcity in diatoms as revealed through metabolomics (Thalassiosira pseudonana study)
- Metabolic consequences of cobalamin scarcity in diatoms as revealed through metabolomics (Navicula pelliculosa study)
- Rabbit plasma metabolomic analysis of Nitroproston: a multi target natural prostaglandin based-drug (Untargeted study)
- Disturbed Microbiota-Metabolites-Immune Interaction Network is Associated with Olfactory Dysfunction in Patients with Chronic Rhinosinusitis
- L-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS positive mode)
- L-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS negative mode)
- Plasma metabolite changes in dairy cows during parturition identified using untargeted metabolomics.
- Searching for Drug Synergy Against Cancer Through Polyamine Metabolism Impairment: Insight Into the Metabolic Effect of Indomethacin on Lung Cancer Cells.
- Changing environments and genetic variation: inbreeding does not compromise short-term physiological responses
Observed in differential profiles
- rps2_wildtype_vs_rps2_A226Y
- G1_Wild_Type_vs_G2_AmBRAcl1
- Wild_Type_vs_tmRNA_Deletion
- Wild_Type_vs_tmRNA_Knockout
- Non_Induced_0_Day_vs_Induced_8_Day
- Non_Induced_0_Day_vs_Induced_8_Day
- Wild_type_vs_hfq
- Phloem_vs_Cambium
- Milk_0h_vs_Whey_72h
- Control_Root_vs_Wild_Type_Root
- RPMI_B36_vs_Pooled_Sera_B36
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- G1_Klebsiella_pneumoniae_AJ218_RPMI_vs_G2_Klebsiella_pneumoniae_AJ218_Pooled_sera
- G1_Pooled_Sera_Blood_4559_vs_G2_RPMI_Glucose_Blood_4559
- G1_RPMI_modified_Blood_M1T1_5448_vs_G2_Pooled_sera_Blood_M1T1_5448
- Control_vs_nsPEF_7_day
- WT_vs_WT_Aco
- Control_vs_CF_high
- Male_vs_Female
- Control_vs_Busulfan_5_mg_kg_RAAE
- Control_vs_Immune_Tolerant
- Control_vs_Immune_Tolerant
- Control_vs_Immune_Tolerant
- Wild_Type_vs_YQ2-gal
- Control_vs_Paramycin
- 16_May_2012_vs_8_June_2012
- Control_vs_Lithogenic_Diet
- Intracellular_vs_Extracellular
- Solanum_habrochaites_leaf_vs_glandular_trichome
- Control_vs_Ethephon_Treatment
- 2:00 AM_Membrane_vs_2:00 AM_Net
- Sham_vs_UIR
- Control_14dpi_vs_Infected_14dpi
- Control_14dpi_vs_Infected_14dpi
- E1777_Intracellular_MidLog_vs_E1777_Intracellular_EarlyStationary
- Normal_control_no_tumor_vs_FH_deficient_RCC
- Hindgut_Control_vs_Lactobacillus_apis
- Embryo_S1_vs_Embryo_S4
- Control_vs_Exercise
- Control_vs_Isoproterenol
- Unfermented_vs_Fermented
- G1_Control_vs_G2_Arginine_Addition
- White_Tea_0h_vs_White_Tea_36h
- Summer_vs_Winter
- Healthy_Control_vs_Osteoarticular_Tuberculosis
- Glu_BW25113_vs_Pyr_BW25113
- Ziyun_No.1_0h_vs_Ziyun_No.1_96h
- Wild_Type_vs_Gene_Knockout
- Normal_vs_Neural_Tube_Defect
- Normal_vs_Neural_Tube_Defect
- Normal_vs_Neural_Tube_Defect
- Sham_vs_HIBD
- Control_vs_CSD
- Control_vs_ZYP_High_Dose
- Dc-N_vs_Dc-HS
- Dcs_N_vs_Dcs_HS
- Healthy_vs_RAS4
- Control_vs_ABA
- Control_0d_vs_Treatment_180d
- Control_0d_vs_Treatment_180d
- Normal_Diet_vs_High-fat_Diet
- Normal_Diet_vs_High-fat_Diet
- Normal_Diet_vs_High-fat_Diet
- CIDP_patient_vs_healthy_control
- CIDP_patient_vs_healthy_control
- G1_Sheep_ASA_SAT_vs_G2_Sheep_GOM_VAT
- DNA-PK_KO_UUO_vs_DNA-PK_KO_Control
- Control_0h_vs_GABA_0h
- Control_vs_Fermented_Mulberry_Leaves
- MC-producing_Exponential_vs_MC-free_Exponential
- Col_ND_15h_vs_Col_ND_27h
- Control_vs_TGF-beta_Treatment
- Control_vs_BP3_Low_Concentration
- Saturating_Limiting_vs_Saturating_Replete
- Navicula_pelliculosa_Saturating_Limiting_vs_Saturating_Replete
- Test_0min_vs_Test_60min
- Normal_vs_Abnormal
- Normal_vs_Abnormal
- SAR-S_vs_SAR-R
- SAR-R_vs_SAR-S
- After_Calving_vs_21_Days_Before_Due_Date
- A549_0uM_vs_A549_1uM
- Inbreeding_Growth_Chamber_0_day_vs_Inbreeding_Growth_Chamber_92_day