Normal_vs_Neural_Tube_Defect

Normal vs Neural_Tube_Defect

p-value ≤ 0.05 260 significant 2025-09-26 00:00:00 Study: MTBLS4893
355 Total Features
260 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS4893_0001_00000003
Linked study
MTBLS4893 — Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Feces metabolomics)
Comparison
Normal vs Neural_Tube_Defect
Group A
Control samples with normal condition.. Provides a reference point for identifying metabolic differences due to neural tube defects.
Group B
Experimental samples with neural tube defect condition.. Crucial for understanding the metabolic changes associated with neural tube defects.
Total features tested
355
Significant features
260
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
DFPAKSUCGFBDDF-UHFFFAOYSA-N β-pyridinecarboxamide down 0.0003777 1.48e-10
XSQUKJJJFZCRTK-UHFFFAOYSA-N H<small><sub>2</sub></small>NC(O)NH<small><sub>2</sub></small> up 74.86 4.57e-14
DCXYFEDJOCDNAF-REOHCLBHSA-N (2<i>S</i>)-2-ammonio-3-carbamoylpropanoate up 1175 7.72e-08
ZMHLUFWWWPBTIU-UHFFFAOYSA-N 4-Hydroxybenzoylglycine down 0.004973 4.88e-09
HDYANYHVCAPMJV-LXQIFKJMSA-N UDP-alpha-D-glucuronate up 49.87 6.49e-10
FEWJPZIEWOKRBE-JCYAYHJZSA-N (2R,3R)-Tartaric acid up 36.59 4.47e-10
HXXFSFRBOHSIMQ-VFUOTHLCSA-N ALPHA-D-GLUCOSE-1-PHOSPHATE down 0.01307 1.21e-07
RXKJFZQQPQGTFL-UHFFFAOYSA-N DHA up 22 5.99e-10
LRQKBLKVPFOOQJ-YFKPBYRVSA-N α-aminocaproic acid up 38.24 2.38e-08
CMWTZPSULFXXJA-VIFPVBQESA-N Naproxen down 0.02244 1.09e-07