Metabolite details
Reactome pathways
- R-HSA-110362 - POLB-Dependent Long Patch Base Excision Repair
- R-HSA-110373 - Resolution of AP sites via the multiple-nucleotide patch replacement pathway
- R-HSA-1257604 - PIP3 activates AKT signaling
- R-HSA-1266738 - Developmental Biology
- R-HSA-1428517 - Aerobic respiration and respiratory electron transport
- R-HSA-1430728 - Metabolism
- R-HSA-1592230 - Mitochondrial biogenesis
- R-HSA-162582 - Signal Transduction
- R-HSA-1640170 - Cell Cycle
- R-HSA-1643685 - Disease
- R-HSA-170834 - Signaling by TGF-beta Receptor Complex
- R-HSA-1852241 - Organelle biogenesis and maintenance
- R-HSA-195721 - Signaling by WNT
- R-HSA-196807 - Nicotinate metabolism
- R-HSA-196849 - Metabolism of water-soluble vitamins and cofactors
- R-HSA-196854 - Metabolism of vitamins and cofactors
- R-HSA-201681 - TCF dependent signaling in response to WNT
- R-HSA-204174 - Regulation of pyruvate dehydrogenase (PDH) complex
- R-HSA-212165 - Epigenetic regulation of gene expression
- R-HSA-212436 - Generic Transcription Pathway
- R-HSA-2151201 - Transcriptional activation of mitochondrial biogenesis
- R-HSA-2173793 - Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
- R-HSA-2173795 - Downregulation of SMAD2/3:SMAD4 transcriptional activity
- R-HSA-2262752 - Cellular responses to stress
- R-HSA-2408508 - Metabolism of ingested SeMet, Sec, MeSec into H2Se
- R-HSA-2408522 - Selenoamino acid metabolism
- R-HSA-2555396 - Mitotic Metaphase and Anaphase
- R-HSA-2995383 - Initiation of Nuclear Envelope (NE) Reformation
- R-HSA-2995410 - Nuclear Envelope (NE) Reassembly
- R-HSA-3371453 - Regulation of HSF1-mediated heat shock response
- R-HSA-3371556 - Cellular response to heat stress
- R-HSA-427359 - SIRT1 negatively regulates rRNA expression
- R-HSA-4641257 - Degradation of AXIN
- R-HSA-5250941 - Negative epigenetic regulation of rRNA expression
- R-HSA-5336415 - Uptake and function of diphtheria toxin
- R-HSA-5339562 - Uptake and actions of bacterial toxins
- R-HSA-5663205 - Infectious disease
- R-HSA-5685939 - HDR through MMEJ (alt-NHEJ)
- R-HSA-5693532 - DNA Double-Strand Break Repair
- R-HSA-5693538 - Homology Directed Repair
- R-HSA-5693567 - HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)
- R-HSA-5693607 - Processing of DNA double-strand break ends
- R-HSA-5696394 - DNA Damage Recognition in GG-NER
- R-HSA-5696398 - Nucleotide Excision Repair
- R-HSA-5696399 - Global Genome Nucleotide Excision Repair (GG-NER)
- R-HSA-6807070 - PTEN Regulation
- R-HSA-68882 - Mitotic Anaphase
- R-HSA-68886 - M Phase
- R-HSA-69278 - Cell Cycle, Mitotic
- R-HSA-70268 - Pyruvate metabolism
- R-HSA-71291 - Metabolism of amino acids and derivatives
- R-HSA-71403 - Citric acid cycle (TCA cycle)
- R-HSA-73857 - RNA Polymerase II Transcription
- R-HSA-73884 - Base Excision Repair
- R-HSA-73894 - DNA Repair
- R-HSA-73933 - Resolution of Abasic Sites (AP sites)
- R-HSA-74160 - Gene expression (Transcription)
- R-HSA-8948751 - Regulation of PTEN stability and activity
- R-HSA-8953897 - Cellular responses to stimuli
- R-HSA-9006925 - Intracellular signaling by second messengers
- R-HSA-9006936 - Signaling by TGFB family members
- R-HSA-9614085 - FOXO-mediated transcription
- R-HSA-9617629 - Regulation of FOXO transcriptional activity by acetylation
- R-HSA-9635486 - Infection with Mycobacterium tuberculosis
- R-HSA-9637679 - Escape of Mtb from the phagocyte
- R-HSA-9637698 - Phagocyte cell death caused by cytosolic Mtb
- R-HSA-9640148 - Infection with Enterobacteria
- R-HSA-9678108 - SARS-CoV-1 Infection
- R-HSA-9679506 - SARS-CoV Infections
- R-HSA-9683610 - Maturation of nucleoprotein
- R-HSA-9683701 - Translation of Structural Proteins
- R-HSA-9694516 - SARS-CoV-2 Infection
- R-HSA-9694631 - Maturation of nucleoprotein
- R-HSA-9694635 - Translation of Structural Proteins
- R-HSA-9730414 - MITF-M-regulated melanocyte development
- R-HSA-9772573 - Late SARS-CoV-2 Infection Events
- R-HSA-9824439 - Bacterial Infection Pathways
- R-HSA-9824446 - Viral Infection Pathways
- R-HSA-9854311 - Maturation of TCA enzymes and regulation of TCA cycle
- R-HSA-9856649 - Transcriptional and post-translational regulation of MITF-M expression and activity
- R-HSA-9861718 - Regulation of pyruvate metabolism
- R-HSA-9956593 - Microbial factors inhibit CASP4 activity
Observed in studies
- Distribution of RESV and its metabolite peaks in mouse tissues after oral and skin administration
- Resveratrol metabolism in HepG2 (human hepatocytes), HaCaT (human keratinocytes), and C2C12 (mouse myoblasts)
- Metabolomics analysis identifies metabolites associated with systemic acquired resistance in Arabidopsis
- Metabolomic Profile of Diet-Induced Obesity Mice in Response to Human and Small Humanin-like Peptide 2 Treatment
- How Does the Seed Pre-germinative Metabolism Fight against Imbibition Damage; Emerging Roles of Fatty Acid Cohort and Antioxidant Defence
- A metabolite roadmap of the wood-forming tissue in Populus tremula (UPLC-MS assay; Wood fibre and ray cell tissue)
- Pb Stress and Ectomycorrhizas: Strong Protective Proteomic Responses in Poplar Roots Inoculated with <i>Paxillus involutus</i> Isolate and Characterized by Low Root Colonization Intensity.
- The impact of slyA on cell metabolism of Salmonella Typhimurium: a joint study of transcriptomics and
- Chemotaxis shapes the microscale organization of the ocean’s microbiome
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Escherichia coli assays)
- Human age-declined saliva metabolic markers determined by LC-MS
- Global Metabonomic and Proteomic Analysis of Human Conjunctival Epithelial Cells (IOBA-NHC) in Response to Hyperosmotic Stress
- Metabolic Dynamics of In Vitro CD8+ T Cell Activation.
- Metabolomic profiling reveals the effects of early-life lactoferrin intervention on protein synthesis, energy production and antioxidative capacity in the liver of suckling piglets
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Klebsiella pneumoniae assays)
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Streptococcus pneumoniae assays)
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Streptococcus pyogenes assays)
- Multi-Omics Analysis Reveals Disturbance of Nanosecond Pulsed Electric Field in the Serum Metabolic Spectrum and Gut Microbiota
- Transcriptional differentiation of Trypanosoma brucei during in vitro acquisition of resistance to acoziborole
- Integrated Analyses of the Gut Microbiota, Intestinal Permeability and Serum Metabolome Phenotype in Rats with Alcohol Withdrawal Syndrome
- Microbial Diversity and Non-volatile Metabolites Profile of Low-Temperature Sausage Stored at Room Temperature
- Metabolic Responses of a Model Green Microalga Euglena gracilis to Different Environmental Stresses
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 21)
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 10)
- Jasmonate-mediated stomatal closure under elevated CO2 revealed by time-resolved metabolomics
- Metabolite profile data of grapevine plants with brown wood streaking and grapevine leaf stripe (esca complex disease) symptoms
- Metabolomics and lipidomics reveal perturbation of sphingolipid metabolism by a novel anti-trypanosomal 3-(oxazolo[4,5-b]pyridine-2-yl)anilide
- Distinct succinate modifying products are clinically diagnostic and prognostic biomarkers for fumarate hydratase deficient renal cell carcinoma
- Gut microbiome drives individual memory variation in bumblebees
- The Manchurian Walnut Genome: Insights into Juglone and Lipid Biosynthesis.
- Mechanical force promotes dimethylarginine dimethylaminohydrolase 1-mediated hydrolysis of the metabolite asymmetric dimethylarginine to enhance bone formation
- Diallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice
- Metabolism Disorder Promotes Isoproterenol-induced Myocardial Injury in Mice with High Temperature and High Humidity and High-Fat Diet
- Exercise-generated β-aminoisobutyric acid (BAIBA) reduces cardiomyocytes metabolic stress and apoptosis caused by mitochondrial dysfunction through the miR-208b/AMPK pathway
- Multi-omic Profiling of Multi-Biosamples Reveals the Role of Amino Acid and Nucleotide Metabolism in Endometrial Cancer
- Transcriptional Shift and Metabolic Adaptations during Leishmania Quiescence Using Stationary Phase and Drug Pressure as Models
- Transcriptome and Metabolome Analyses Reveal Differences in Terpenoid and Flavonoid Biosynthesis in Cryptomeria fortunei Needles Across Different Seasons
- Effects of Radiofrequency Field from 5G Communications on fecal microbiome and metabolome profiles in mice
- Comparative Analysis of Host Metabolic Alterations in Murine Malaria Models with Uncomplicated or Severe Malaria
- Phosphoproteomic and Metabolomic Profiling Uncovers the Roles of CcPmk1 in the Pathogenicity of <i>Cytospora chrysosperma</i>
- AMPK activation orchestrated replicative senescence of periodontal ligament stem cells via regulating metabolomics
- Cardiac disruption of SDHAF4-mediated mitochondrial complex II assembly promotes dilated cardiomyopathy.
- Integrated Metabolomics and Transcriptomics Analyses Reveal Anthocyanin and Carotenoid Biosynthesis Involved in Color Development in Willow Bark
- Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Feces metabolomics)
- Sodium Butyrate mediates Histone Crotonylation and Alleviated Neonatal Rats Hypoxic-Ischemic Brain Injury Through Gut-Brain Axis (untargeted fecal metabolomics)
- Interaction between Cervical Microbiota and Host Gene Regulation in Caesarean Section Scar Diverticulum
- Mechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis
- Effects of Centella asiatica extract on antioxidant status and liver metabolome of rotenone-treated rats using GC-MS
- PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis.
- Integrated Proteomic and Metabolomic Analyses Show Differential Effects of Glucose Availability in Marine <i>Synechococcus</i> and <i>Prochlorococcus</i>.
- Diverse metabolic reactions activated during 58-hr fasting are revealed by non-targeted metabolomic analysis of human blood.
- Metabolic disorder and intestinal microflora dysbiosis in chronic inflammatory demyelinating polyradiculoneuropathy
- DNA-PKcs drives CKD progression by activating TAF7/RAPTOR/mTORC1 signaling-mediated metabolic reprogramming
- Metabolic Changes of Maternal Uterine Fluid, Uterus, and Plasma during the Peri-implantation Period of Early Pregnancy in Mice.
- Flow cytometry has a significant impact on the cellular metabolome (CE-MS assay)
- GABA regulates IL-1β production in macrophages
- FSCN1 as a new druggable target in adrenocortical carcinoma
- Transcriptomics and metabolomics analysis reveal the anti-oxidation and immune boosting effects of mulberry leaves in growing mutton sheep
- A Pilot Characterization of the Human Chronobiome
- Comparative metabolomic analysis of exudates of microcystin-producing and microcystin-free Microcystis aeruginosa strains
- Extracellular-acidosis restricts one-carbon metabolism and preserves T cell stemness
- Effects of Yulin Tong Bu formula on modulating gut microbiota and fecal metabolite interactions in mice with polycystic ovary syndrome
- PatA mediates biofilm formation and drugs resistance through regulating the synthesis of glycolipids and lipids in mycobacterium PatA mediates a novel mycolic acid synthesis pathway and regulates biofilm formation in mycobacterium
- Metabolic changes associated with tick-microbe interactions
- TGF-β uncouples glycolysis and inflammation in macrophages and controls the survival during sepsis
- Genetic mapping and molecular mechanism behind color variation in the Asian vine snake
- Integrated Proteomics and Metabolomics Analysis Reveals Differential Lipid Metabolism in HUVEC under high and low shear stress
- Disturbed Microbiota-Metabolites-Immune Interaction Network is Associated with Olfactory Dysfunction in Patients with Chronic Rhinosinusitis
- L-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS positive mode)
- L-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS negative mode)
- Metabolic effects of an aspartate aminotransferase-inhibitor on two T-cell lines
- Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency.
- Plasma metabolite changes in dairy cows during parturition identified using untargeted metabolomics.
- Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites (Blood fraction)
- Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites (Blood plasma and RBC fractions)
Observed in differential profiles
- Control_Oral_Blood_vs_RESV_Oral_Blood
- Control_Oral_Blood_vs_RESV_Oral_Blood
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- Local_Leaf_Control_vs_Local_Leaf_Avr
- Water_vs_HNG
- Water_vs_HNG
- Water_vs_HNG
- Water_vs_HNG
- Dry_Seed_vs_8h_Imbibed_Seed
- Fiber_vs_Ray
- NM-control_vs_NM-Pb
- slyA_vs_wild_type
- Alexandrium_vs_Amphidinium
- RPMI_B36_vs_Pooled_Sera_B36
- Old_vs_Young
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- 280_mOsm_vs_480_mOsm
- 280_mOsm_vs_480_mOsm
- Control_Day_8_vs_Lactoferrin_Day_8
- G1_Klebsiella_pneumoniae_AJ218_RPMI_vs_G2_Klebsiella_pneumoniae_AJ218_Pooled_sera
- G1_Pooled_Sera_Blood_4559_vs_G2_RPMI_Glucose_Blood_4559
- G1_RPMI_modified_Blood_M1T1_5448_vs_G2_Pooled_sera_Blood_M1T1_5448
- Control_vs_nsPEF_7_day
- WT_vs_WT_Aco
- Alcohol_Treatment_vs_Control
- Control_vs_Day_12
- Control_vs_Paramycin
- Sham_vs_UIR
- Sham_vs_UIR
- 400ppm_0min_vs_800ppm_60min
- Control_vs_Asymptomatic
- Control_vs_OXPA_Treatment
- Control_vs_OXPA_Treatment
- Normal_control_no_tumor_vs_FH_deficient_RCC
- Hindgut_Control_vs_Lactobacillus_apis
- Embryo_S1_vs_Embryo_S4
- Control_vs_Exercise
- G1_PBS_vs_G2_DSS
- Control_vs_Isoproterenol
- Sham_vs_Heart_Failure_Sedentary
- Sham_vs_Heart_Failure_Sedentary
- Control_vs_Endometrial_Cancer
- AMAD_Log_vs_AMAE_Sta
- Summer_vs_Winter
- Sham_vs_Radiofrequency
- Uninfected_BALB/c_vs_Plasmodium_yoelii_17XL_BALB/c
- CcPmk1_vs_Wild_type
- Passage_4_vs_Passage_20
- Wild_type_vs_Knock_out
- Purple_vs_Green
- Normal_vs_Neural_Tube_Defect
- Normal_vs_Neural_Tube_Defect
- Sham_vs_HIBD
- Control_vs_CSD
- Control_vs_ZYP_High_Dose
- Control_vs_Treatment
- MCF-7_WT_vs_MCF-7_PKM2_KO
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- Blood_10h_vs_Blood_58h
- CIDP_patient_vs_healthy_control
- DNA-PK_KO_UUO_vs_DNA-PK_KO_Control
- Pregnant_Blood_Plasma_Day_1_vs_Pregnant_Blood_Plasma_Day_4
- Control_0h_vs_GABA_0h
- Ctrl_vs_Ab
- Control_Vehicle_vs_FSCN1_Knockout_Vehicle
- Control_vs_Fermented_Mulberry_Leaves
- Plasma_0h_vs_Plasma_48h
- MC-producing_Exponential_vs_MC-free_Exponential
- Control_vs_Lactic_Acid
- Control_vs_PCOS
- wild_type_vs_patA_deletion
- Uninfected_1h_vs_Anaplasma_phagocytophilum_1h
- Control_vs_TGF-beta_Treatment
- Yellow_Skin_vs_Green_Skin
- Low_Shear_Stress_vs_High_Shear_Stress
- Normal_vs_Abnormal
- Normal_vs_Abnormal
- SAR-S_vs_SAR-R
- SAR-R_vs_SAR-S
- JURKAT_Control_vs_JURKAT_Treatment
- WT_vs_ErbB2_KI
- After_Calving_vs_21_Days_Before_Due_Date
- Human_Blood_vs_Human_Plasma
- Human_Blood_vs_Human_Plasma
- Human_Blood_vs_Human_Plasma
- Blood_vs_Plasma
- Blood_vs_Plasma