Metabolism Disorder Promotes Isoproterenol-induced Myocardial Injury in Mice with High Temperature and High Humidity and High-Fat Diet

Study details

Source ID

https://identifiers.org/metabolights:MTBLS3886

Title

Metabolism Disorder Promotes Isoproterenol-induced Myocardial Injury in Mice with High Temperature and High Humidity and High-Fat Diet

Summary

Study on myocardial injury in mice model.

Observation

Myocardial injury induced by ISO, high temperature, humidity, and fat diet.

Findings

Nontargeted metabolomics reveals serum metabolism profile for mechanism elucidation.

Disease terms

metabolism disorder, cardiovascular disease, cardiovascular diseases, phlegm-damp syndrome, myocardial injury, Metabolism disorder, Phlegm-damp syndrome, left ventricular hypertrophy, fibrosis, syndrome, Chinese Medicine

Gene terms

—

Chemical terms

SMs, proline, Sphingosine, isoproterenol, arginine, L-Arginine, Isoproterenol, sphingolipid, glycerophospholipid, lysoPCs, ISO

Organisms

mouse, mice

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS3886.

{
  "@type": "Dataset",
  "integmet_study": "MTBLS3886",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:D012493",
    "https://identifiers.org/mesh:D011392",
    "https://identifiers.org/mesh:D013110",
    "https://identifiers.org/mesh:D007545",
    "https://identifiers.org/mesh:D001120",
    "https://identifiers.org/mesh:D013107",
    "https://identifiers.org/mesh:D020404",
    "https://identifiers.org/mesh:C006065"
  ],
  "mesh_chemical_pubtator_kw": [
    "SMs",
    "proline",
    "Sphingosine",
    "isoproterenol",
    "arginine",
    "L-Arginine",
    "Isoproterenol",
    "sphingolipid",
    "glycerophospholipid",
    "lysoPCs",
    "ISO"
  ],
  "mesh_disease_id": [
    "https://identifiers.org/mesh:D008659",
    "https://identifiers.org/mesh:D002318",
    "https://identifiers.org/mesh:D013577",
    "https://identifiers.org/mesh:D009202",
    "https://identifiers.org/mesh:D017379",
    "https://identifiers.org/mesh:D005355",
    "https://identifiers.org/mesh:C562377"
  ],
  "mesh_disease_pubtator_kw": [
    "metabolism disorder",
    "cardiovascular disease",
    "cardiovascular diseases",
    "phlegm-damp syndrome",
    "myocardial injury",
    "Metabolism disorder",
    "Phlegm-damp syndrome",
    "left ventricular hypertrophy",
    "fibrosis",
    "syndrome",
    "Chinese Medicine"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:10090"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "mouse",
    "mice"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS3886",
  "study_findings": "Nontargeted metabolomics reveals serum metabolism profile for mechanism elucidation.",
  "study_observation": "Myocardial injury induced by ISO, high temperature, humidity, and fat diet.",
  "study_summary": "Study on myocardial injury in mice model.",
  "study_title_original": "Metabolism Disorder Promotes Isoproterenol-induced Myocardial Injury in Mice with High Temperature and High Humidity and High-Fat Diet"
}