Comparative Analysis of Host Metabolic Alterations in Murine Malaria Models with Uncomplicated or Severe Malaria

Study details

Source ID

https://identifiers.org/metabolights:MTBLS4387

Title

Comparative Analysis of Host Metabolic Alterations in Murine Malaria Models with Uncomplicated or Severe Malaria

Summary

Metabolic changes in murine malaria models studied.

Observation

Host metabolic pathways and metabolites in murine malaria models.

Findings

Shared metabolic attributes in malaria; specific metabolite changes in severe and cerebral malaria.

Disease terms

cerebral malaria, uncomplicated malaria, Severe malaria, malaria infections, Malaria, malaria disease, malaria, Severe Malaria, severe malaria

Gene terms

—

Chemical terms

hippurate, 20-hydroxy-leukotriene B4, histidine, arginine, pipecolate, bile pigments, ornithine, sphingolipid, steroid hormones, phenylalanine, valine, bile acids

Organisms

Plasmodium, mice, human

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS4387.

{
  "@type": "Dataset",
  "integmet_study": "MTBLS4387",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:C030514",
    "https://identifiers.org/mesh:C031571",
    "https://identifiers.org/mesh:D006639",
    "https://identifiers.org/mesh:D001120",
    "https://identifiers.org/mesh:C031345",
    "https://identifiers.org/mesh:D001654",
    "https://identifiers.org/mesh:D009952",
    "https://identifiers.org/mesh:D013107",
    "https://identifiers.org/mesh:D013256",
    "https://identifiers.org/mesh:D010649",
    "https://identifiers.org/mesh:D014633",
    "https://identifiers.org/mesh:D001647"
  ],
  "mesh_chemical_pubtator_kw": [
    "hippurate",
    "20-hydroxy-leukotriene B4",
    "histidine",
    "arginine",
    "pipecolate",
    "bile pigments",
    "ornithine",
    "sphingolipid",
    "steroid hormones",
    "phenylalanine",
    "valine",
    "bile acids"
  ],
  "mesh_disease_id": [
    "https://identifiers.org/mesh:D016779",
    "https://identifiers.org/mesh:D008288"
  ],
  "mesh_disease_pubtator_kw": [
    "cerebral malaria",
    "uncomplicated malaria",
    "Severe malaria",
    "malaria infections",
    "Malaria",
    "malaria disease",
    "malaria",
    "Severe Malaria",
    "severe malaria"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:418103",
    "https://identifiers.org/taxonomy:10090",
    "https://identifiers.org/taxonomy:9606"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "Plasmodium",
    "mice",
    "human"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS4387",
  "study_findings": "Shared metabolic attributes in malaria; specific metabolite changes in severe and cerebral malaria.",
  "study_observation": "Host metabolic pathways and metabolites in murine malaria models.",
  "study_summary": "Metabolic changes in murine malaria models studied.",
  "study_title_original": "Comparative Analysis of Host Metabolic Alterations in Murine Malaria Models with Uncomplicated or Severe Malaria"
}