Diff Profiles › MTBLS4387_0004_00000001

Uninfected_BALB/c_vs_Plasmodium_yoelii_17XL_BALB/c

Uninfected_BALB/c vs Plasmodium_yoelii_17XL_BALB/c

p-value ≤ 0.05 21 significant 2025-09-26 00:00:00 Study: MTBLS4387
21 Total Features
21 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS4387_0004_00000001
Linked study
MTBLS4387 — Comparative Analysis of Host Metabolic Alterations in Murine Malaria Models with Uncomplicated or Severe Malaria
Comparison
Uninfected_BALB/c vs Plasmodium_yoelii_17XL_BALB/c
Group A
Uninfected BALB/c mice serum samples. Provides baseline metabolic profile for comparison with infected BALB/c samples.
Group B
BALB/c mice infected with Plasmodium yoelii 17XL. Allows for the study of metabolic changes due to Plasmodium yoelii 17XL infection in BALB/c mice.
Total features tested
21
Significant features
21
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
PFNFFQXMRSDOHW-UHFFFAOYSA-N 4,9-diaza-1,12-dodecanediamine up 638.4 0.00548
OCNLJCZKGHKJGF-NQYRMHKHSA-M Adenosylcobyrinic acid a,c-diamide down 0.07192 0.000125
XMRPGKVKISIQBV-XWOJZHJZSA-N 5β-dihydroprogesterone down 0.2442 4.94e-06
RWBRUCCWZPSBFC-RXRZZTMXSA-N 20alpha-Hydroxyprogesterone down 0.2442 4.94e-06
XMRPGKVKISIQBV-BJMCWZGWSA-N 3,20-allopregnanedione down 0.2442 4.94e-06
ORNBQBCIOKFOEO-QGVNFLHTSA-N 3beta-Hydroxypregn-5-en-20-one down 0.2442 4.94e-06
WHOOUMGHGSPMGR-UHFFFAOYSA-N Indole-3-acetaldehyde up 3.244 5.33e-05
QZBYOYPROVGOGE-UHFFFAOYSA-N N-(3-Aminopropyl)cadaverine up 3.251 9.39e-05
MXNRLFUSFKVQSK-QMMMGPOBSA-O N6,N6,N6-Trimethyl-L-lysine up 3.207 0.000118
MBWXNTAXLNYFJB-NKFFZRIASA-N 2-methyl-3-phytyl-1,4-naphthoquinone down 0.1204 0.00853