Diff Profiles › MTBLS2721_0001_00000007

Control_vs_CF_high

Control vs CF_high

p-value ≤ 0.05 46 significant 2025-09-26 00:00:00 Study: MTBLS2721
110 Total Features
46 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS2721_0001_00000007
Linked study
MTBLS2721 — Efficacy of Zhuyu Pill Intervention in a Cholestasis Rat Model: Mutual Effects on Fecal Metabolism and Microbial Diversity
Comparison
Control vs CF_high
Group A
Control group with no treatment applied.. Provides baseline data for comparison with treated groups.
Group B
High dose Zhuyu Pill treatment group.. Evaluates the effect of high dose Zhuyu Pill on cholestasis.
Total features tested
110
Significant features
46
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
RNHPWASTISTGIP-UHFFFAOYSA-N 6-(2-benzoyloxy-5-prop-2-enylphenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid down 3.547e-10 0.000636
SZSLZBYOLTYIOE-UHFFFAOYSA-N 3-[7-(uran-3-yl)-1,8,15,15-tetramethyl-5,18-dioxo-3,6,14-trioxapentacyclo[9.7.0.02,4.02,8.012,16]octadecan-12-yl]-3-hydroxypropanoic acid down 1.077e-10 0.00613
ISLXOQLYOVJTQL-UHFFFAOYSA-N 5,7-dihydroxy-2-[7-hydroxy-2-(hydroxymethyl)-2-(4-methylpent-3-enyl)chromen-6-yl]-2,3-dihydrochromen-4-one down 0.000426 3.15e-05
UVISYWPYGSRGJF-UHFFFAOYSA-N 3,4,5-trihydroxy-6-[2-[9-(3-methylbut-2-enoyloxy)-2-oxo-8,9-dihydrouro[2,3-h]chromen-8-yl]propan-2-yloxy]oxane-2-carboxylic acid down 0.001401 6.22e-06
WDLWHQDACQUCJR-PBFPGSCMSA-N Cefprozil anhydrous down 0.0001621 0.000568
JFHIFUDPQDOKTR-UHFFFAOYSA-N 3,4,5-trihydroxy-6-[2-(2-methoxy-4-prop-2-enylphenoxy)carbonylphenoxy]oxane-2-carboxylic acid down 0.0001591 0.00114
HZJBDSMAAFNHHL-HSQINTTRSA-N [(3S,4S,6S)-3,4,5-trihydroxy-6-[3-(4-methoxyphenyl)-4-oxochromen-7-yl]oxyoxan-2-yl]methyl acetate down 0.009876 1.28e-05
HWAJASVMTDEFJN-MKBHYRRPSA-N (1R,2R,4S,7S,8S,11R,12R,18R)-7-(uran-3-yl)-13-hydroxy-1,8,12,17,17-pentamethyl-3,6,16-trioxapentacyclo[9.9.0.02,4.02,8.012,18]icosane-5,15,20-trione down 0.0008272 0.00358
DPTWUYFOEZBIEX-UHFFFAOYSA-N 2-[4,5-dihydroxy-6-(hydroxymethyl)-2-(2,4,5-trihydroxyoxan-3-yl)oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol down 0.003058 0.00361
HVDGDHBAMCBBLR-PBHICJAKSA-N 3,4-bis[(3-hydroxyphenyl)methyl]oxolan-2-one up 5.81 6.77e-08