Diff Profiles › MTBLS1167_0001_00000001

G1_Wild_Type_vs_G2_AmBRAcl1

Wild_Type vs AmBRAcl1

p-value ≤ 0.05 9 significant 2025-09-26 00:00:00 Study: MTBLS1167
14 Total Features
9 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS1167_0001_00000001
Linked study
MTBLS1167 — Untargeted metabolomics to understand the basis of phenotypic differences in amphotericin B-resistant Leishmania parasites
Comparison
Wild_Type vs AmBRAcl1
Group A
Wild type Leishmania mexicana samples. Baseline group for comparison with resistant samples to understand resistance mechanisms.
Group B
AmB-resistant L. mexicana line AmBRAcl1. Helps in understanding the resistance mechanisms in AmBRAcl1 line.
Total features tested
14
Significant features
9
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
MTCFGRXMJLQNBG-UHFFFAOYSA-N serine zwitterion up 2.208 0.00015
BYSGBSNPRWKUQH-UJDJLXLFSA-N — up 2.328 0.00186
GUBGYTABKSRVRQ-PICCSMPSSA-N Malzzucker down 0.5639 0.000181
FYGDTMLNYKFZSV-PXXRMHSHSA-N Amylotriose up 2.323 0.00291
JVTAAEKCZFNVCJ-UWTATZPHSA-N (−)-lactic acid down 0.5846 0.00137
KDYFGRWQOYBRFD-UHFFFAOYSA-N E363 down 0.6343 0.0011
BIRSGZKFKXLSJQ-SQOUGZDYSA-N 6-Phospho-D-gluconate up 1.601 0.00274
MVMSCBBUIHUTGJ-GDJBGNAASA-N Guanosine diphosphomannose up 1.535 0.0139
FTNIPWXXIGNQQF-XHCCAYEESA-N β-<small>D</small>-Glc<em>p</em>-(1→4)-β-<small>D</small>-Glc<em>p</em>-(1→4)-β-<small>D</small>-Glc<em>p</em>-(1→4)-β-<small>D</small>-Glc<em>p</em>-(1→4)-<small>D</small>-Glc<em>p</em> up 1.553 0.0412