Diff Profiles › MTBLS2721_0003_00000007

Control_vs_CF_high

Control vs CF_high

p-value ≤ 0.05 89 significant 2025-09-26 00:00:00 Study: MTBLS2721
216 Total Features
89 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS2721_0003_00000007
Linked study
MTBLS2721 — Efficacy of Zhuyu Pill Intervention in a Cholestasis Rat Model: Mutual Effects on Fecal Metabolism and Microbial Diversity
Comparison
Control vs CF_high
Group A
Control group with no treatment applied.. Provides baseline data for comparison with treated groups.
Group B
High dose Zhuyu Pill treatment group.. Evaluates the effect of high dose Zhuyu Pill on cholestasis.
Total features tested
216
Significant features
89
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
WRIYPTGFYKBSFU-UHFFFAOYSA-N [butoxy(ethylsulanyl)phosphoryl]sulanylmethylbenzene down 0.002086 2.2e-05
DAEYIVCTQUFNTM-ABAIWWIYSA-N <em>N</em>-{[(3<i>R</i>)-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1<em>H</em>-isochromen-7-yl]carbonyl}-<small>L</small>-phenylalanine down 0.001098 9.48e-05
KBDSLGBFQAGHBE-MSGMIQHVSA-N Evodin down 0.0001128 0.0015
LKPQNZRGGNOPPU-UHFFFAOYSA-N 3-methoxy-2-phenyluro[2,3-h]chromen-4-one down 0.0003972 0.00117
ASUSBMNYRHGZIG-UHFFFAOYSA-N N-Methylserotonin down 0.01177 1.9e-05
TWUOPSPDYDPTLF-UHFFFAOYSA-N 6-[[9,10-dihydroxy-4-(hydroxymethyl)-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-3,4-dihydroxy-5-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-2-carboxylic acid down 0.008497 0.000166
AOYGNVHBYGMHGR-UHFFFAOYSA-N 6,11-dihydroxy-10-methoxy-3,3,12-trimethylpyrano[2,3-c]acridin-7-one down 0.001905 0.00495
MHMJDFLOHGJHIJ-UMNDTTGPSA-N (4R)-4-[(3R,5R,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid up 119.9 0.00153
QUCQEUCGKKTEBI-UHFFFAOYSA-N 5,6-Dihydro-2,3,9,10-tetramethoxydibenzo[a,g]quinolizinium down 0.001925 0.00855
SWALXCKAJQTSAC-UHFFFAOYSA-N 6,11-dihydroxy-6,20-dimethyl-4,8-dioxa-20-azapentacyclo[10.8.0.02,9.03,7.014,19]icosa-1(12),2(9),10,14,16,18-hexaen-13-one down 0.0003791 0.0231