Diff Profiles › MTBLS3628_0002_00000004

Normal_control_no_tumor_vs_FH_deficient_RCC

Normal_control_no_tumor vs FH_deficient_RCC

p-value ≤ 0.05 18 significant 2025-09-26 00:00:00 Study: MTBLS3628
85 Total Features
18 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS3628_0002_00000004
Linked study
MTBLS3628 — Distinct succinate modifying products are clinically diagnostic and prognostic biomarkers for fumarate hydratase deficient renal cell carcinoma
Comparison
Normal_control_no_tumor vs FH_deficient_RCC
Group A
Samples from healthy individuals with no tumor.. Provides a reference for identifying metabolic changes specific to RCC.
Group B
Samples from patients with FH-deficient renal cell carcinoma.. Key group for identifying metabolic biomarkers associated with FH-deficient RCC.
Total features tested
85
Significant features
18
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
LCTONWCANYUPML-UHFFFAOYSA-N Acetylformic acid down 0.3038 3.13e-05
HDTRYLNUVZCQOY-MFAKQEFJSA-N — up 5.843 0.00242
GHCZAUBVMUEKKP-GYPHWSFCSA-N glycine chenodeoxycholate up 4.979 0.0046
VFUIRAVTUVCQTF-BSOWLZGZSA-N 3α-hydroxy-5α-androstan-17-one glucuronide down 0.4656 2.27e-05
KIQMCGMHGVXDFW-UHFFFAOYSA-N 1-methyl-hypoxanthine up 2.194 4.56e-05
UDMBCSSLTHHNCD-KQYNXXCUSA-N Adenosine-5'-monophosphoric acid down 0.4499 0.000858
OPTASPLRGRRNAP-UHFFFAOYSA-N Zytosin up 2.229 0.00295
NIDVTARKFBZMOT-PEBGCTIMSA-N 4-acetyl-1-(β-<small>D</small>-ribofuranosyl)cytosine up 2.306 0.00453
ZOOLJLSXNRZLDH-KTKRTIGZSA-N (1-hydroxy-3-phosphonooxypropan-2-yl) (Z)-octadec-9-enoate down 0.597 0.000289
INPGLFHHFHOGRM-BYPYZUCNSA-N (2S)-2-(propanoylamino)propanoic acid up 2.116 0.00484