Diff Profiles › MTBLS3628_0003_00000004

Normal_control_no_tumor_vs_FH_deficient_RCC

Normal_control_no_tumor vs FH_deficient_RCC

p-value ≤ 0.05 22 significant 2025-09-26 00:00:00 Study: MTBLS3628
70 Total Features
22 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS3628_0003_00000004
Linked study
MTBLS3628 — Distinct succinate modifying products are clinically diagnostic and prognostic biomarkers for fumarate hydratase deficient renal cell carcinoma
Comparison
Normal_control_no_tumor vs FH_deficient_RCC
Group A
Samples from healthy individuals with no tumor.. Provides a reference for identifying metabolic changes specific to RCC.
Group B
Samples from patients with FH-deficient renal cell carcinoma.. Key group for identifying metabolic biomarkers associated with FH-deficient RCC.
Total features tested
70
Significant features
22
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
ZTNFQEXYTMNFHG-SOFXVBFTSA-N Phosphatidylserine(36:4) up 4.914 4.62e-05
IULWELDCBXQXED-DWOSIAKHSA-N 1-Stearoyl-2-eicsoic acid up 3.129 5.06e-05
MWONMGIZXLAUBR-QUBHBNJHSA-N 18:1-18:2-PS up 3.222 0.00035
SSRRIJSEUKHYFB-DFCPKGTFSA-N — up 7.344 0.031
SKGJYUSTRBEFGF-IPXPVBFCSA-N — up 4.079 0.0106
YDTWOEYVDRKKCR-KNERPIHHSA-N 1-octadecanoyl-2-[(9<i>Z</i>,12<i>Z</i>)-octadecadienoyl]-<em>sn</em>-glycero-3-phosphoethanolamine zwitterion up 3.876 0.0118
GMJZFMGAYZSOKQ-YBHUKKJQSA-N [(2R)-1-[2-aminoethoxy(hydroxy)phosphoryl]oxy-3-pentadecanoyloxypropan-2-yl] (4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate down 0.3419 0.0054
AGTPCXBHIGMTEU-NREGDSCDSA-N Phosphatidylserine(18:0/18:2w6) up 3.3 0.0228
RPLIGUADJKNWQR-MBYQFZCISA-N — down 0.4514 0.00537
HNFSZKRUPTYBOQ-ZDYOIFAYSA-N PE(40:4) up 2.5 0.0153