Normal_control_no_tumor_vs_FH_deficient_RCC

Profile details

Identifier: MTBLS3628_0004_00000004
Linked study: MTBLS3628 — Distinct succinate modifying products are clinically diagnostic and prognostic biomarkers for fumarate hydratase deficient renal cell carcinoma
Comparison: Normal_control_no_tumor vs FH_deficient_RCC
Group A: Samples from healthy individuals with no tumor.. Provides a reference for identifying metabolic changes specific to RCC.
Group B: Samples from patients with FH-deficient renal cell carcinoma.. Key group for identifying metabolic biomarkers associated with FH-deficient RCC.
Total features tested: 254
Significant features: 57
p-value threshold: 0.05
Ratio threshold (upper): 1.5
Ratio threshold (lower): 1/1.5
Date created: 2025-09-26 00:00:00

Metabolite ID (InChI Key)	Name	Direction	Ratio	p-value
DPPYJZPUMHOJFQ-IASQADCASA-N	[(2R)-2-[(6Z,9Z,12Z,15Z)-octadeca-6,9,12,15-tetraenoyl]oxy-3-pentadecanoyloxypropyl] 2-(trimethylazaniumyl)ethyl phosphate	up	3.477	1.22e-06
LFUDDCMNKWEORN-ZXEGGCGDSA-N	GPC(16:1)	down	0.311	7.7e-07
XOLZNHXNFMEUGA-MCPSVCLNSA-N	—	down	0.2331	1.66e-05
BHOBAXXVADYYDE-WJOKGBTCSA-N	—	down	0.2504	1.84e-05
RETPVUGMYRRYPF-SGFDTVKUSA-N	[(2R)-1-[2-aminoethoxy(hydroxy)phosphoryl]oxy-3-tetradecanoyloxypropan-2-yl] (Z)-docos-13-enoate	up	4.539	0.000174
VZPPRGZNTVUBLP-UKNPSHDRSA-N	[(2R)-2-[(6Z,9Z,12Z)-octadeca-6,9,12-trienoyl]oxy-3-pentadecanoyloxypropyl] 2-(trimethylazaniumyl)ethyl phosphate	up	6.231	0.00105
VRVDEVSSPPTZQJ-JKCKFMQZSA-N	[(2R)-2-hydroxy-3-[(Z)-nonadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate	down	0.3618	4.49e-06
UJMUDAMKHIWLCZ-OTHSKKDYSA-N	PC 15:0/20:5(5Z,8Z,11Z,14Z,17Z)	up	4.176	0.000405
VXUOFDJKYGDUJI-OAQYLSRUSA-N	1-myristoyl-glycero-3-phosphocholine	down	0.2711	0.00022
YTQRLPWDUKCRNO-MULSWCQISA-N	[(2S)-1-hydroxy-3-pentadecanoyloxypropan-2-yl] (6Z,9Z,12Z)-octadeca-6,9,12-trienoate	down	0.261	0.000976