Diff Profiles › MTBLS6886_0001_00000001

Control_vs_TGF-beta_Treatment

Control vs TGF-beta_Treatment

p-value ≤ 0.05 29 significant 2025-09-26 00:00:00 Study: MTBLS6886
131 Total Features
29 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS6886_0001_00000001
Linked study
MTBLS6886 — TGF-β uncouples glycolysis and inflammation in macrophages and controls the survival during sepsis
Comparison
Control vs TGF-beta_Treatment
Group A
Macrophages treated with control conditions. Provides baseline data for comparison with TGF-beta treated samples
Group B
Macrophages treated with TGF-beta. Key group for assessing the impact of TGF-beta on macrophage metabolism
Total features tested
131
Significant features
29
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
IISAHBYOIFITKV-UHFFFAOYSA-N 1-(2-amino-3-hydroxypropanoyl)-4-hydroxypyrrolidine-2-carboxylic acid up 6.653 0.0172
JRLGPAXAGHMNOL-LURJTMIESA-N (2<i>S</i>)-2-acetamido-5-ammoniopentanoate up 6.625 0.0183
UFIVEPVSAGBUSI-REOHCLBHSA-N L-Dihydroorotic acid down 0.3654 0.000732
COLNVLDHVKWLRT-QMMMGPOBSA-N β-phenyl-<small>L</small>-alanine up 1.896 1.9e-05
SRNWOUGRCWSEMX-TYASJMOZSA-N ribose adenosinediphosphate up 2.426 0.0012
ACNQSIOMZUBKCK-FWSONLODSA-N — down 0.4186 0.00108
FDJKUWYYUZCUJX-PGIATKPXSA-N — down 0.46 0.000631
RTQMRTSPTLIIHM-KEOHHSTQSA-N Phosphoribosyl-AMP up 2.723 0.00633
MCGXOCXFFNKASF-FMDGEEDCSA-N N-Acetyl-beta-D-glucosaminylamine up 4.964 0.0439
LFTYTUAZOPRMMI-ZYQOOJPVSA-N UDP-N-acetyl-D-mannosamine down 0.5875 8.7e-05