Metabolite details
Reactome pathways
- R-HSA-1430728 - Metabolism
- R-HSA-15869 - Metabolism of nucleotides
- R-HSA-1643685 - Disease
- R-HSA-168138 - Toll Like Receptor 9 (TLR9) Cascade
- R-HSA-168181 - Toll Like Receptor 7/8 (TLR7/8) Cascade
- R-HSA-168249 - Innate Immune System
- R-HSA-168256 - Immune System
- R-HSA-168898 - Toll-like Receptor Cascades
- R-HSA-382551 - Transport of small molecules
- R-HSA-425397 - Transport of vitamins, nucleosides, and related molecules
- R-HSA-425407 - SLC-mediated transmembrane transport
- R-HSA-5260271 - Diseases of Immune System
- R-HSA-5602358 - Diseases associated with the TLR signaling cascade
- R-HSA-5619063 - Defective SLC29A3 causes histiocytosis-lymphadenopathy plus syndrome (HLAS)
- R-HSA-5619102 - SLC transporter disorders
- R-HSA-5619115 - Disorders of transmembrane transporters
- R-HSA-5668914 - Diseases of metabolism
- R-HSA-5686938 - Regulation of TLR by endogenous ligand
- R-HSA-74217 - Purine salvage
- R-HSA-74259 - Purine catabolism
- R-HSA-83936 - Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
- R-HSA-8956319 - Nucleotide catabolism
- R-HSA-8956321 - Nucleotide salvage
- R-HSA-9735763 - Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine
- R-HSA-9735786 - Nucleotide catabolism defects
- R-HSA-9735804 - Diseases of nucleotide metabolism
- R-HSA-975110 - TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
- R-HSA-975138 - TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
- R-HSA-975155 - MyD88 dependent cascade initiated on endosome
- R-HSA-9824856 - Defective regulation of TLR7 by endogenous ligand
Observed in studies
- Absence of tmRNA Increases the Persistence to Cefotaxime and the Intercellular Accumulation of Metabolite GlcNAc in <i>Aeromonas veronii</i>.
- Absence of tmRNA increases the persistence to cefotaxime by upregulating the metabolites GlcNAc in Aeromonas veronii
- Distribution of RESV and its metabolite peaks in mouse tissues after oral and skin administration
- Resveratrol metabolism in HepG2 (human hepatocytes), HaCaT (human keratinocytes), and C2C12 (mouse myoblasts)
- Hfq Regulates Efflux Pump Expression and Purine Metabolic Pathway to Increase the Trimethoprim Resistance in Aeromonas veronii
- Jejunal inflammatory cytokines, barrier proteins and microbiome-metabolome responses to early supplementary feeding of Bamei suckling piglets
- How Does the Seed Pre-germinative Metabolism Fight against Imbibition Damage; Emerging Roles of Fatty Acid Cohort and Antioxidant Defence
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Escherichia coli assays)
- Metabolic Dynamics of In Vitro CD8+ T Cell Activation.
- Metabolomic profiling reveals the effects of early-life lactoferrin intervention on protein synthesis, energy production and antioxidative capacity in the liver of suckling piglets
- Model-driven multi-omic data analysis elucidates metabolic immunomodulators of macrophage activation
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Klebsiella pneumoniae assays)
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Streptococcus pyogenes assays)
- Metabolomic Insights into the Browning of the Peel of Bagging ‘Rui Xue’ Apple Fruit
- Multi-Omics Analysis Reveals Disturbance of Nanosecond Pulsed Electric Field in the Serum Metabolic Spectrum and Gut Microbiota
- Fat Deposition in the Muscle of Female and Male Yak and the Correlation of Yak Meat Quality with Fat
- Host autophagy mediates organ wasting and nutrient mobilization for tumor growth.
- Red-Fleshed Apple Anthocyanin Extracts Attenuate Male Reproductive System Dysfunction Caused by Busulfan in Mice (Mouse blood plasma; UPLC-MS/MS assays)
- Transcriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth
- Metabolic Responses of a Model Green Microalga Euglena gracilis to Different Environmental Stresses
- Metabolites from surface seawater collected in Narragansett Bay
- Changes and correlations of intestinal flora and liver metabolite profiles in mice with gallstones
- A Phosphate starvation response gene (psr1-like) is present in Micromonas pusilla and other marine algae and coordinates the metabolic response to phosphate deficiency
- Multiomics of tomato glandular trichomes reveals distinct features of central carbon metabolism supporting high productivity of specialized metabolites
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 21)
- Metabolomics dataset of PPAR-pan treated rat liver (acyl-carnitine and aqueous metabolite assays)
- High complexity and diel dynamics of planktonic microbiome revealed by multi-omics in Taihu, China
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 10)
- Jasmonate-mediated stomatal closure under elevated CO2 revealed by time-resolved metabolomics
- Multiple biochemical indices and metabolomics of Clonorchis sinensis provide a novel interpretation of biomarkers
- Chronic sleep loss sensitizes Drosophila melanogaster to nitrogen stress
- Plant-to-plant variability in root metabolite profiles of 19 Arabidopsis thaliana accessions is substance-class dependent
- Metabolite profile data of grapevine plants with brown wood streaking and grapevine leaf stripe (esca complex disease) symptoms
- Analysis of Growth Phases of Enterotoxigenic Escherichia coli Reveals a Distinct Transition Phase before Entry into Early Stationary Phase with Shifts in Tryptophan, Fucose, and Putrescine Metabolism and Degradation of Neurotransmitter Precursors
- Metabolomic analysis of the mechanism of action of yerba mate extract on Salmonella Typhimurium
- Gut microbiome drives individual memory variation in bumblebees
- The Manchurian Walnut Genome: Insights into Juglone and Lipid Biosynthesis.
- Evaluation of algorithms for multiple alignment of GCxGC-MS data
- Mechanical force promotes dimethylarginine dimethylaminohydrolase 1-mediated hydrolysis of the metabolite asymmetric dimethylarginine to enhance bone formation
- Diallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice
- Appropriate taxonomic classification of intestinal microbiome by 16S rRNA gene targeting metagenomic approach
- Long-term low-dose ionizing radiation induced chromosome-aberration-specific metabolic phenotype changes in radiation workers
- Exercise-generated β-aminoisobutyric acid (BAIBA) reduces cardiomyocytes metabolic stress and apoptosis caused by mitochondrial dysfunction through the miR-208b/AMPK pathway
- Multi-omic Profiling of Multi-Biosamples Reveals the Role of Amino Acid and Nucleotide Metabolism in Endometrial Cancer
- Metabolic profilings of rat INS-1 β-cells under changing levels of essential amino acids
- Characterization of white tea metabolome: comparison against green and black tea by a nontargeted metabolomics approach.
- Transcriptional Shift and Metabolic Adaptations during Leishmania Quiescence Using Stationary Phase and Drug Pressure as Models
- Transcriptome and Metabolome Analyses Reveal Differences in Terpenoid and Flavonoid Biosynthesis in Cryptomeria fortunei Needles Across Different Seasons
- Effects of Radiofrequency Field from 5G Communications on fecal microbiome and metabolome profiles in mice
- Homeostasis of the biosynthetic E. coli metabolome
- Comparative Metabolomic Profiling of Compatible and Incompatible Interactions Between Potato and Phytophthora infestans
- Auricularia auricula polysaccharides reduce obesity in mice through gut commensal Papillibacter cinnamivorans
- Cardiac disruption of SDHAF4-mediated mitochondrial complex II assembly promotes dilated cardiomyopathy.
- Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors
- Integrated Metabolomics and Transcriptomics Analyses Reveal Anthocyanin and Carotenoid Biosynthesis Involved in Color Development in Willow Bark
- Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Feces metabolomics)
- Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Brain tissue metabolomics)
- Sodium Butyrate mediates Histone Crotonylation and Alleviated Neonatal Rats Hypoxic-Ischemic Brain Injury Through Gut-Brain Axis (untargeted fecal metabolomics)
- Interaction between Cervical Microbiota and Host Gene Regulation in Caesarean Section Scar Diverticulum
- Mechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis
- Multiomic analysis revealed the potential role of rumen microbes in heat stress
- Effect of heat stress on serum enzyme activity, antioxidant capacity and immune parameter metabolomics datasets in Holstein cows at different growth stages
- PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis.
- Alterations in the gut microbiota and metabolomics of seafarers after a six-month sea voyage
- Bile acid is a significant host factor shaping the gut microbiome of diet induced obese mice (untargeted metabolome profile assay)
- Integrated Proteomic and Metabolomic Analyses Show Differential Effects of Glucose Availability in Marine <i>Synechococcus</i> and <i>Prochlorococcus</i>.
- DNA-PKcs drives CKD progression by activating TAF7/RAPTOR/mTORC1 signaling-mediated metabolic reprogramming
- GABA regulates IL-1β production in macrophages
- FSCN1 as a new druggable target in adrenocortical carcinoma
- Transcriptomics and metabolomics analysis reveal the anti-oxidation and immune boosting effects of mulberry leaves in growing mutton sheep
- A Pilot Characterization of the Human Chronobiome
- Extracellular-acidosis restricts one-carbon metabolism and preserves T cell stemness
- Metabolic changes associated with tick-microbe interactions
- TGF-β uncouples glycolysis and inflammation in macrophages and controls the survival during sepsis
- Unraveling the metabolic effects of benzophenone-3 on the endosymbiotic dinoflagellate Cladocopium goreaui
- Genetic mapping and molecular mechanism behind color variation in the Asian vine snake
- Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction
- Disturbed Microbiota-Metabolites-Immune Interaction Network is Associated with Olfactory Dysfunction in Patients with Chronic Rhinosinusitis
- L-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS positive mode)
- L-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS negative mode)
- Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency.
- Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites (Blood fraction)
- Searching for Drug Synergy Against Cancer Through Polyamine Metabolism Impairment: Insight Into the Metabolic Effect of Indomethacin on Lung Cancer Cells.
- Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites (Blood plasma and RBC fractions)
Observed in differential profiles
- Wild_Type_vs_tmRNA_Deletion
- Wild_Type_vs_tmRNA_Knockout
- Wild_Type_vs_tmRNA_Knockout
- Control_Oral_Blood_vs_RESV_Oral_Blood
- Control_Oral_Blood_vs_RESV_Oral_Blood
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- Wild_type_vs_hfq
- Supplementary_feeding_vs_Control
- Dry_Seed_vs_8h_Imbibed_Seed
- RPMI_B36_vs_Pooled_Sera_B36
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- Control_Day_8_vs_Lactoferrin_Day_8
- G1_Klebsiella_pneumoniae_AJ218_RPMI_vs_G2_Klebsiella_pneumoniae_AJ218_Pooled_sera
- G1_Klebsiella_pneumoniae_AJ218_RPMI_vs_G2_Klebsiella_pneumoniae_AJ218_Pooled_sera
- G1_RPMI_modified_Blood_M1T1_5448_vs_G2_Pooled_sera_Blood_M1T1_5448
- Non_Bagged_Fruits_vs_Bagged_Fruits_With_Browning
- Control_vs_Lipopolysaccharide_stimulated
- Control_vs_nsPEF_7_day
- Male_vs_Female
- G1_Frt_Ctrl_Day_6_vs_G3_Rasv12_Scrib_Day_6
- Control_vs_Busulfan_5_mg_kg_RAAE
- Wild_Type_vs_YQ2-gal
- Wild_Type_vs_YQ2-gal
- Control_vs_Paramycin
- 16_May_2012_vs_8_June_2012
- 16_May_2012_vs_8_June_2012
- Control_vs_Lithogenic_Diet
- Intracellular_vs_Extracellular
- Solanum_habrochaites_leaf_vs_glandular_trichome
- Sham_vs_UIR
- 2:00 AM_Membrane_vs_2:00 AM_Net
- Control_vs_High
- Sham_vs_UIR
- 400ppm_0min_vs_800ppm_60min
- Control_14dpi_vs_Infected_14dpi
- Control_14dpi_vs_Infected_14dpi
- Iso31_Control_vs_Fumin_Homozygous_Sleep_Mutants
- G1_Ws_vs_G2_Wu
- Control_vs_Asymptomatic
- E1777_Intracellular_MidLog_vs_E1777_Intracellular_EarlyStationary
- No_Tea_0min_vs_Tea_240min
- Hindgut_Control_vs_Lactobacillus_apis
- Embryo_S1_vs_Embryo_S4
- Control_vs_Exercise
- G1_PBS_vs_G2_DSS
- Untreated_vs_Antibiotic_Treated
- Untreated_vs_Antibiotic_Treated
- CC406_t2_vs_Stm6Glc4_t2
- LLIR_vs_Control
- Sham_vs_Heart_Failure_Sedentary
- Sham_vs_Heart_Failure_Sedentary
- Control_vs_Endometrial_Cancer
- G1_Control_vs_G2_Arginine_Addition
- White_Tea_0h_vs_White_Tea_36h
- AMAD_Log_vs_AMAE_Sta
- Summer_vs_Winter
- Summer_vs_Winter
- Sham_vs_Radiofrequency
- Glu_BW25113_vs_Pyr_BW25113
- Ziyun_No.1_0h_vs_Ziyun_No.1_96h
- Basal_vs_High_Fat
- Wild_type_vs_Knock_out
- Wild_Type_vs_Gene_Knockout
- Purple_vs_Green
- Normal_vs_Neural_Tube_Defect
- Normal_vs_Neural_Tube_Defect
- Normal_vs_Neural_Tube_Defect
- Sham_vs_HIBD
- Control_vs_CSD
- Control_vs_ZYP_High_Dose
- Dc-N_vs_Dc-HS
- Dcs_N_vs_Dcs_HS
- Control_0d_vs_Treatment_180d
- Control_0d_vs_Treatment_180d
- MCF-7_WT_vs_MCF-7_PKM2_KO
- Normal_Diet_vs_High-fat_Diet
- Normal_Diet_vs_High-fat_Diet
- Normal_Diet_vs_High-fat_Diet
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- DNA-PK_KO_UUO_vs_DNA-PK_KO_Control
- Control_0h_vs_GABA_0h
- Control_Vehicle_vs_FSCN1_Knockout_Vehicle
- Control_vs_Fermented_Mulberry_Leaves
- Plasma_0h_vs_Plasma_48h
- Control_vs_Lactic_Acid
- Uninfected_1h_vs_Anaplasma_phagocytophilum_1h
- Control_vs_TGF-beta_Treatment
- Control_vs_BP3_Low_Concentration
- Yellow_Skin_vs_Green_Skin
- Arginine_Replenished_Ctrl_vs_Arginine_Starved_48h
- Normal_vs_Abnormal
- Normal_vs_Abnormal
- SAR-S_vs_SAR-R
- SAR-R_vs_SAR-S
- WT_vs_ErbB2_KI
- A549_0uM_vs_A549_1uM
- Human_Blood_vs_Human_Plasma
- Human_Blood_vs_Human_Plasma
- Human_Blood_vs_Human_Plasma
- Blood_vs_Plasma
- Blood_vs_Plasma