Metabolite details
Reactome pathways
- R-HSA-1430728 - Metabolism
- R-HSA-382551 - Transport of small molecules
- R-HSA-425407 - SLC-mediated transmembrane transport
- R-HSA-549127 - SLC-mediated transport of organic cations
- R-HSA-71288 - Creatine metabolism
- R-HSA-71291 - Metabolism of amino acids and derivatives
Observed in studies
- Biological effect of chronic mistranslation in mammalian cells
- Sex-Differences in Colon Cancer Metabolism Reveal A Novel Subphenotype
- Distribution of RESV and its metabolite peaks in mouse tissues after oral and skin administration
- Resveratrol metabolism in HepG2 (human hepatocytes), HaCaT (human keratinocytes), and C2C12 (mouse myoblasts)
- Metabolomic Profile of Diet-Induced Obesity Mice in Response to Human and Small Humanin-like Peptide 2 Treatment
- Four layer multi-omics reveals molecular responses to aneuploidy in <i>Leishmania</i>
- Large-Scale Plasma Analysis Revealed New Mechanisms and Molecules Associated with the Host Response to SARS-CoV-2.
- Physiological extremes of the human blood metabolome: A metabolomics analysis of highly glycolytic, oxidative, and anabolic athletes
- Human age-declined saliva metabolic markers determined by LC-MS
- Metabolic Dynamics of In Vitro CD8+ T Cell Activation.
- Model-driven multi-omic data analysis elucidates metabolic immunomodulators of macrophage activation
- Transcriptional differentiation of Trypanosoma brucei during in vitro acquisition of resistance to acoziborole
- Integrated Analyses of the Gut Microbiota, Intestinal Permeability and Serum Metabolome Phenotype in Rats with Alcohol Withdrawal Syndrome
- Host autophagy mediates organ wasting and nutrient mobilization for tumor growth.
- Transcriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth
- Microbial Diversity and Non-volatile Metabolites Profile of Low-Temperature Sausage Stored at Room Temperature
- Dietary carbohydrate and protein levels affect the growth performance of juvenile peanut worm (Sipunculus nudus): an LC–MS-based metabolomics study
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 21)
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 10)
- Multiple biochemical indices and metabolomics of Clonorchis sinensis provide a novel interpretation of biomarkers
- Metabolite profile data of grapevine plants with brown wood streaking and grapevine leaf stripe (esca complex disease) symptoms
- Metabolomics and lipidomics reveal perturbation of sphingolipid metabolism by a novel anti-trypanosomal 3-(oxazolo[4,5-b]pyridine-2-yl)anilide
- Distinct succinate modifying products are clinically diagnostic and prognostic biomarkers for fumarate hydratase deficient renal cell carcinoma
- Diallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice
- Appropriate taxonomic classification of intestinal microbiome by 16S rRNA gene targeting metagenomic approach
- Exercise-generated β-aminoisobutyric acid (BAIBA) reduces cardiomyocytes metabolic stress and apoptosis caused by mitochondrial dysfunction through the miR-208b/AMPK pathway
- Metabolic profilings of rat INS-1 β-cells under changing levels of essential amino acids
- Transcriptional Shift and Metabolic Adaptations during Leishmania Quiescence Using Stationary Phase and Drug Pressure as Models
- Novel Potential Diagnostic Serum Biomarkers of Metabolomics in Osteoarticular Tuberculosis Patients: A Preliminary Study
- Cardiac disruption of SDHAF4-mediated mitochondrial complex II assembly promotes dilated cardiomyopathy.
- Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors
- Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Feces metabolomics)
- Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Brain tissue metabolomics)
- Sodium Butyrate mediates Histone Crotonylation and Alleviated Neonatal Rats Hypoxic-Ischemic Brain Injury Through Gut-Brain Axis (untargeted fecal metabolomics)
- Interaction between Cervical Microbiota and Host Gene Regulation in Caesarean Section Scar Diverticulum
- Stage-specific roles of microbial dysbiosis and metabolic disorders in rheumatoid arthritis
- PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis.
- Bile acid is a significant host factor shaping the gut microbiome of diet induced obese mice (untargeted metabolome profile assay)
- Diverse metabolic reactions activated during 58-hr fasting are revealed by non-targeted metabolomic analysis of human blood.
- Metabolic disorder and intestinal microflora dysbiosis in chronic inflammatory demyelinating polyradiculoneuropathy
- 4-Octyl itaconate as a metabolite derivative inhibits inflammation via alkylation of STING
- DNA-PKcs drives CKD progression by activating TAF7/RAPTOR/mTORC1 signaling-mediated metabolic reprogramming
- Metabolic Changes of Maternal Uterine Fluid, Uterus, and Plasma during the Peri-implantation Period of Early Pregnancy in Mice.
- GABA regulates IL-1β production in macrophages
- Flow cytometry has a significant impact on the cellular metabolome (GC-MS assay)
- FSCN1 as a new druggable target in adrenocortical carcinoma
- Transcriptomics and metabolomics analysis reveal the anti-oxidation and immune boosting effects of mulberry leaves in growing mutton sheep
- A Pilot Characterization of the Human Chronobiome
- Comparative metabolomic analysis of exudates of microcystin-producing and microcystin-free Microcystis aeruginosa strains
- Metabolic changes associated with tick-microbe interactions
- Bacterial Pathogens Hijack the Innate Immune Response by Activation of the Reverse Transsulfuration Pathway.
- Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice
- Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction
- Disturbed Microbiota-Metabolites-Immune Interaction Network is Associated with Olfactory Dysfunction in Patients with Chronic Rhinosinusitis
- L-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS positive mode)
- L-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS negative mode)
- Metabolic effects of an aspartate aminotransferase-inhibitor on two T-cell lines
- Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency.
- Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites (Blood fraction)
- Searching for Drug Synergy Against Cancer Through Polyamine Metabolism Impairment: Insight Into the Metabolic Effect of Indomethacin on Lung Cancer Cells.
- Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites (Blood plasma and RBC fractions)
- Novel Minor Groove Binders cure animal African trypanosomiasis in an in vivo mouse model
Observed in differential profiles
- rps2_wildtype_vs_rps2_A226Y
- mennormal_vs_menLCCstage1
- Control_Oral_Blood_vs_RESV_Oral_Blood
- Control_Oral_Blood_vs_RESV_Oral_Blood
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- HepG2_0uM_vs_HepG2_200uM
- Water_vs_HNG
- Water_vs_HNG
- Water_vs_HNG
- Water_vs_HNG
- Nepalese_BPK173_vs_Nepalese_BPK178
- non_COVID_19_healthy_vs_non_critical_COVID_19
- Control_Baseline_vs_Control_Post-Exercise
- Old_vs_Young
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- Control_vs_Lipopolysaccharide_stimulated
- WT_vs_WT_Aco
- Alcohol_Treatment_vs_Control
- G1_Frt_Ctrl_Day_6_vs_G3_Rasv12_Scrib_Day_6
- Wild_Type_vs_YQ2-gal
- Control_vs_Day_12
- Diet_D2_vs_Diet_D5
- Sham_vs_UIR
- Sham_vs_UIR
- Control_14dpi_vs_Infected_14dpi
- Control_14dpi_vs_Infected_14dpi
- Control_vs_Asymptomatic
- Control_vs_OXPA_Treatment
- Control_vs_OXPA_Treatment
- Normal_control_no_tumor_vs_FH_deficient_RCC
- G1_PBS_vs_G2_DSS
- Untreated_vs_Antibiotic_Treated
- Untreated_vs_Antibiotic_Treated
- Sham_vs_Heart_Failure_Sedentary
- Sham_vs_Heart_Failure_Sedentary
- G1_Control_vs_G2_Arginine_Addition
- AMAD_Log_vs_AMAE_Sta
- Healthy_Control_vs_Osteoarticular_Tuberculosis
- Wild_type_vs_Knock_out
- Wild_Type_vs_Gene_Knockout
- Normal_vs_Neural_Tube_Defect
- Normal_vs_Neural_Tube_Defect
- Sham_vs_HIBD
- Control_vs_CSD
- Healthy_vs_RAS4
- Healthy_vs_RAS4
- MCF-7_WT_vs_MCF-7_PKM2_KO
- Normal_Diet_vs_High-fat_Diet
- Normal_Diet_vs_High-fat_Diet
- Normal_Diet_vs_High-fat_Diet
- Blood_10h_vs_Blood_58h
- CIDP_patient_vs_healthy_control
- Control_vs_DMXAA16h
- DNA-PK_KO_UUO_vs_DNA-PK_KO_Control
- Pregnant_Blood_Plasma_Day_1_vs_Pregnant_Blood_Plasma_Day_4
- Control_0h_vs_GABA_0h
- Ctrl_vs_Ab
- Control_Vehicle_vs_FSCN1_Knockout_Vehicle
- Control_vs_Fermented_Mulberry_Leaves
- Plasma_0h_vs_Plasma_48h
- MC-producing_Exponential_vs_MC-free_Exponential
- MC-producing_Exponential_vs_MC-free_Exponential
- Uninfected_1h_vs_Anaplasma_phagocytophilum_1h
- G1_Infected_Treated_vs_G2_Infected_Untreated
- ASD_Fecal_vs_TD_Fecal
- Arginine_Replenished_Ctrl_vs_Arginine_Starved_48h
- Normal_vs_Abnormal
- SAR-S_vs_SAR-R
- SAR-R_vs_SAR-S
- JURKAT_Control_vs_JURKAT_Treatment
- WT_vs_ErbB2_KI
- A549_0uM_vs_A549_1uM
- Human_Blood_vs_Human_Plasma
- Human_Blood_vs_Human_Plasma
- Human_Blood_vs_Human_Plasma
- MGB234_Treatment_vs_DMSO_Control
- MGB234_Treatment_vs_DMSO_Control
- Blood_vs_Plasma
- Blood_vs_Plasma