Large-Scale Plasma Analysis Revealed New Mechanisms and Molecules Associated with the Host Response to SARS-CoV-2.

Study details

Source ID

https://identifiers.org/metabolights:MTBLS1866

Title

Large-Scale Plasma Analysis Revealed New Mechanisms and Molecules Associated with the Host Response to SARS-CoV-2.

Summary

Plasma analysis reveals COVID-19 host response mechanisms.

Observation

Host response to SARS-CoV-2 infection

Findings

Identified biomarkers, lipid alterations, and potential therapeutic targets for COVID-19.

Disease terms

Coronavirus Disease 2019, infection, COVID-19, SARS-CoV-2 infection, deaths

Gene terms

PLA2, phospholipase A2

Chemical terms

oleic acid, tryptophan, phosphatidylethanolamine, tricarboxylic acid, tyrosine, aminoacyl-tRNA, arachidonic acid, fatty acids, lipids, porphyrins, TCA, phosphatidylcholine, triglycerides, phenylalanine

Organisms

patients, SARS-CoV-2

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS1866.

{
  "@type": "Dataset",
  "go_id": [
    "https://identifiers.org/GO:0006778",
    "https://identifiers.org/GO:0019369",
    "https://identifiers.org/GO:0006094",
    "https://identifiers.org/GO:0006558",
    "https://identifiers.org/GO:0001897",
    "https://identifiers.org/GO:0006629",
    "https://identifiers.org/GO:0004623",
    "https://identifiers.org/GO:0006099"
  ],
  "go_kw": [
    "porphyrin metabolism",
    "arachidonic acid metabolism",
    "gluconeogenesis",
    "phenylalanine metabolism",
    "pathogenesis",
    "lipid metabolism",
    "phospholipase A2 activity",
    "tricarboxylic acid cycle"
  ],
  "integmet_study": "MTBLS1866",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:D019301",
    "https://identifiers.org/mesh:D014364",
    "https://identifiers.org/mesh:C483858",
    "https://identifiers.org/mesh:D014233",
    "https://identifiers.org/mesh:D014443",
    "https://identifiers.org/mesh:D012346",
    "https://identifiers.org/mesh:D016718",
    "https://identifiers.org/mesh:D005227",
    "https://identifiers.org/mesh:D008055",
    "https://identifiers.org/mesh:D011166",
    "https://identifiers.org/mesh:D010713",
    "https://identifiers.org/mesh:D014280",
    "https://identifiers.org/mesh:D010649"
  ],
  "mesh_chemical_pubtator_kw": [
    "oleic acid",
    "tryptophan",
    "phosphatidylethanolamine",
    "tricarboxylic acid",
    "tyrosine",
    "aminoacyl-tRNA",
    "arachidonic acid",
    "fatty acids",
    "lipids",
    "porphyrins",
    "TCA",
    "phosphatidylcholine",
    "triglycerides",
    "phenylalanine"
  ],
  "mesh_disease_id": [
    "https://identifiers.org/mesh:D000086382",
    "https://identifiers.org/mesh:D007239",
    "https://identifiers.org/mesh:D003643"
  ],
  "mesh_disease_pubtator_kw": [
    "Coronavirus Disease 2019",
    "infection",
    "COVID-19",
    "SARS-CoV-2 infection",
    "deaths"
  ],
  "mesh_gene_id": [
    "https://identifiers.org/ncbigene:5319"
  ],
  "mesh_gene_pubtator_kw": [
    "PLA2",
    "phospholipase A2"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:9606",
    "https://identifiers.org/taxonomy:2697049"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "patients",
    "SARS-CoV-2"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS1866",
  "study_findings": "Identified biomarkers, lipid alterations, and potential therapeutic targets for COVID-19.",
  "study_observation": "Host response to SARS-CoV-2 infection",
  "study_summary": "Plasma analysis reveals COVID-19 host response mechanisms.",
  "study_title_original": "Large-Scale Plasma Analysis Revealed New Mechanisms and Molecules Associated with the Host Response to SARS-CoV-2."
}