MGB234_Treatment_vs_DMSO_Control

MGB234_Treatment vs DMSO_Control

p-value ≤ 0.05 16 significant 2025-09-26 00:00:00 Study: MTBLS882
16 Total Features
16 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS882_0001_00000001
Linked study
MTBLS882 — Novel Minor Groove Binders cure animal African trypanosomiasis in an in vivo mouse model
Comparison
MGB234_Treatment vs DMSO_Control
Group A
Samples treated with MGB234 compound.. Key group for assessing the efficacy of the MGB234 compound.
Group B
Samples treated with DMSO as a control.. Provides baseline for comparison with MGB234 treatment.
Total features tested
16
Significant features
16
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
MXHRCPNRJAMMIM-SHYZEUOFSA-N Deoxyuridine up 7.321 0.000144
DTERQYGMUDWYAZ-ZETCQYMHSA-N N(6)-ACETYLLYSINE up 3.55 4.93e-06
FDGQSTZJBFJUBT-UHFFFAOYSA-N Purine-6-ol up 4.564 3.83e-05
LXNHXLLTXMVWPM-UHFFFAOYSA-N vitamin B<small><sub>6</sub></small> up 6.713 0.000382
OPTASPLRGRRNAP-UHFFFAOYSA-N Zytosin up 3.668 1.62e-05
UHDGCWIWMRVCDJ-XVFCMESISA-N 4-amino-1-β-<small>D</small>-ribofuranosylpyrimidin-2(1<em>H</em>)-one up 3.074 7.34e-05
AUTOLBMXDDTRRT-UHFFFAOYSA-N Dethiobiotin up 2.327 1.69e-05
DRTQHJPVMGBUCF-XVFCMESISA-N u up 2.315 8.2e-05
YDGMGEXADBMOMJ-LURJTMIESA-N NG,NG-Dimethyl-L-arginine up 2.227 5.49e-05
JSRLJPSBLDHEIO-SHYZEUOFSA-N dUMP up 2.256 0.000338