Metabolite details
Reactome pathways
- R-HSA-1222556 - ROS and RNS production in phagocytes
- R-HSA-1430728 - Metabolism
- R-HSA-15869 - Metabolism of nucleotides
- R-HSA-1643685 - Disease
- R-HSA-168138 - Toll Like Receptor 9 (TLR9) Cascade
- R-HSA-168181 - Toll Like Receptor 7/8 (TLR7/8) Cascade
- R-HSA-168249 - Innate Immune System
- R-HSA-168256 - Immune System
- R-HSA-168898 - Toll-like Receptor Cascades
- R-HSA-5260271 - Diseases of Immune System
- R-HSA-5602358 - Diseases associated with the TLR signaling cascade
- R-HSA-5668914 - Diseases of metabolism
- R-HSA-5686938 - Regulation of TLR by endogenous ligand
- R-HSA-74217 - Purine salvage
- R-HSA-74259 - Purine catabolism
- R-HSA-8956319 - Nucleotide catabolism
- R-HSA-8956321 - Nucleotide salvage
- R-HSA-9735763 - Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine
- R-HSA-9735786 - Nucleotide catabolism defects
- R-HSA-9735804 - Diseases of nucleotide metabolism
- R-HSA-975110 - TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
- R-HSA-975138 - TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
- R-HSA-975155 - MyD88 dependent cascade initiated on endosome
- R-HSA-9824856 - Defective regulation of TLR7 by endogenous ligand
Observed in studies
- Biological effect of chronic mistranslation in mammalian cells
- Hfq Regulates Efflux Pump Expression and Purine Metabolic Pathway to Increase the Trimethoprim Resistance in Aeromonas veronii
- Bioaccumulation of therapeutic drugs by human gut bacteria: cross-feeding metabolite analysis (FIA-MS) (E.rectale;S.salivarius assays)
- How Does the Seed Pre-germinative Metabolism Fight against Imbibition Damage; Emerging Roles of Fatty Acid Cohort and Antioxidant Defence
- Metabolic Dynamics of In Vitro CD8+ T Cell Activation.
- Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Klebsiella pneumoniae assays)
- Multi-Omics Analysis Reveals Disturbance of Nanosecond Pulsed Electric Field in the Serum Metabolic Spectrum and Gut Microbiota
- Changes and correlations of intestinal flora and liver metabolite profiles in mice with gallstones
- Anti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 10)
- Jasmonate-mediated stomatal closure under elevated CO2 revealed by time-resolved metabolomics
- Metabolite profile data of grapevine plants with brown wood streaking and grapevine leaf stripe (esca complex disease) symptoms
- Analysis of Growth Phases of Enterotoxigenic Escherichia coli Reveals a Distinct Transition Phase before Entry into Early Stationary Phase with Shifts in Tryptophan, Fucose, and Putrescine Metabolism and Degradation of Neurotransmitter Precursors
- Gut microbiome drives individual memory variation in bumblebees
- The Manchurian Walnut Genome: Insights into Juglone and Lipid Biosynthesis.
- Mechanical force promotes dimethylarginine dimethylaminohydrolase 1-mediated hydrolysis of the metabolite asymmetric dimethylarginine to enhance bone formation
- Diallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice
- Appropriate taxonomic classification of intestinal microbiome by 16S rRNA gene targeting metagenomic approach
- Transcriptome and Metabolome Analyses Reveal Differences in Terpenoid and Flavonoid Biosynthesis in Cryptomeria fortunei Needles Across Different Seasons
- Effects of Radiofrequency Field from 5G Communications on fecal microbiome and metabolome profiles in mice
- Integrated metabolomics and transcriptome revealed the effect of fermented Lycium barbarum residue promoting Ovis aries immunity
- AMPK activation orchestrated replicative senescence of periodontal ligament stem cells via regulating metabolomics
- Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors
- Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Feces metabolomics)
- Sodium Butyrate mediates Histone Crotonylation and Alleviated Neonatal Rats Hypoxic-Ischemic Brain Injury Through Gut-Brain Axis (untargeted fecal metabolomics)
- Mechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis
- PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis.
- Alterations in the gut microbiota and metabolomics of seafarers after a six-month sea voyage
- Bile acid is a significant host factor shaping the gut microbiome of diet induced obese mice (untargeted metabolome profile assay)
- Integrated Proteomic and Metabolomic Analyses Show Differential Effects of Glucose Availability in Marine <i>Synechococcus</i> and <i>Prochlorococcus</i>.
- Flow cytometry has a significant impact on the cellular metabolome (General LC-MS assay)
- GABA regulates IL-1β production in macrophages
- Transcriptomics and metabolomics analysis reveal the anti-oxidation and immune boosting effects of mulberry leaves in growing mutton sheep
- Metabolic changes associated with tick-microbe interactions
- TGF-β uncouples glycolysis and inflammation in macrophages and controls the survival during sepsis
- Unraveling the metabolic effects of benzophenone-3 on the endosymbiotic dinoflagellate Cladocopium goreaui
- Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction
- Disturbed Microbiota-Metabolites-Immune Interaction Network is Associated with Olfactory Dysfunction in Patients with Chronic Rhinosinusitis
- Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency.
Observed in differential profiles
- rps2_wildtype_vs_rps2_A226Y
- Wild_type_vs_hfq
- G4_Eubacterium_rectale_DMSO_30_vs_G3_Eubacterium_rectale_Duloxetine_47
- Dry_Seed_vs_8h_Imbibed_Seed
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
- G1_Klebsiella_pneumoniae_AJ218_RPMI_vs_G2_Klebsiella_pneumoniae_AJ218_Pooled_sera
- Control_vs_nsPEF_7_day
- Control_vs_Lithogenic_Diet
- Sham_vs_UIR
- 400ppm_0min_vs_800ppm_60min
- Control_vs_Asymptomatic
- E1777_Intracellular_MidLog_vs_E1777_Intracellular_EarlyStationary
- Hindgut_Control_vs_Lactobacillus_apis
- Embryo_S1_vs_Embryo_S4
- Control_vs_Exercise
- G1_PBS_vs_G2_DSS
- Untreated_vs_Antibiotic_Treated
- Untreated_vs_Antibiotic_Treated
- Summer_vs_Winter
- Sham_vs_Radiofrequency
- RCON_vs_RFW
- Passage_4_vs_Passage_20
- Wild_Type_vs_Gene_Knockout
- Normal_vs_Neural_Tube_Defect
- Normal_vs_Neural_Tube_Defect
- Sham_vs_HIBD
- Control_vs_ZYP_High_Dose
- Control_0d_vs_Treatment_180d
- MCF-7_WT_vs_MCF-7_PKM2_KO
- Normal_Diet_vs_High-fat_Diet
- Normal_Diet_vs_High-fat_Diet
- Normal_Diet_vs_High-fat_Diet
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- SS120_Control_vs_SS120_5mM
- Ctrl_vs_Ab
- Control_0h_vs_GABA_0h
- Control_vs_Fermented_Mulberry_Leaves
- Uninfected_1h_vs_Anaplasma_phagocytophilum_1h
- Control_vs_TGF-beta_Treatment
- Control_vs_BP3_Low_Concentration
- Arginine_Replenished_Ctrl_vs_Arginine_Starved_48h
- Normal_vs_Abnormal
- WT_vs_ErbB2_KI