4-hydroxy-2-oxoglutaric acid

Metabolite details

Identifier

WXSKVKPSMAHCSG-UHFFFAOYSA-N

InChI Key

WXSKVKPSMAHCSG-UHFFFAOYSA-N

IUPAC name

2-hydroxy-4-oxopentanedioic acid

Preferred name

4-hydroxy-2-oxoglutaric acid

INN name

—

Synonym

4-Hydroxy-2-oxoglutaric acid

ChEBI

CHEBI:30923

Reactome pathways

• No Reactome pathways listed for this metabolite.

Observed in studies

• Immune variation leads to diverse outcomes in human malaria
• Bioaccumulation of therapeutic drugs by human gut bacteria: cross-feeding metabolite analysis (FIA-MS) (E.rectale;S.salivarius assays)
• Transcriptional differentiation of Trypanosoma brucei during in vitro acquisition of resistance to acoziborole
• Microbial Diversity and Non-volatile Metabolites Profile of Low-Temperature Sausage Stored at Room Temperature
• Metabolomics and lipidomics reveal perturbation of sphingolipid metabolism by a novel anti-trypanosomal 3-(oxazolo[4,5-b]pyridine-2-yl)anilide
• Integrated Proteomic and Metabolomic Analyses Show Differential Effects of Glucose Availability in Marine <i>Synechococcus</i> and <i>Prochlorococcus</i>.
• Extracellular-acidosis restricts one-carbon metabolism and preserves T cell stemness
• Unraveling the metabolic effects of benzophenone-3 on the endosymbiotic dinoflagellate Cladocopium goreaui

Observed in differential profiles

• IFN_responder_Pre-infection_vs_Diagnosis
• IFN_responder_Pre-infection_vs_Diagnosis
• G4_Eubacterium_rectale_DMSO_30_vs_G3_Eubacterium_rectale_Duloxetine_47
• WT_vs_WT_Aco
• Control_vs_Day_12
• Control_vs_OXPA_Treatment
• Control_vs_OXPA_Treatment
• SS120_Control_vs_SS120_5mM
• SS120_Control_vs_SS120_5mM
• SS120_Control_vs_SS120_5mM
• SS120_Control_vs_SS120_5mM
• SS120_Control_vs_SS120_5mM
• SS120_Control_vs_SS120_5mM
• Control_vs_Lactic_Acid
• Control_vs_BP3_Low_Concentration