mitomycin C

Metabolite details

Identifier

NWIBSHFKIJFRCO-WUDYKRTCSA-N

InChI Key

NWIBSHFKIJFRCO-WUDYKRTCSA-N

IUPAC name

[(1aS,8S,8aR,8bS)-6-amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate

Preferred name

mitomycin C

INN name

—

Synonym

Mutamycin

ChEBI

CHEBI:27504

Reactome pathways

• R-HSA-6783310 - Fanconi Anemia Pathway
• R-HSA-73894 - DNA Repair
• R-HSA-9750126 - Drug-induced formation of DNA interstrand crosslinks

Observed in studies

• Diallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice
• Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Feces metabolomics)
• Mechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis
• Metabolic disorder and intestinal microflora dysbiosis in chronic inflammatory demyelinating polyradiculoneuropathy
• Metabolomics Investigation of Dietary Effects on Flesh Quality in Grass Carp (Ctenopharyngodon idellus)

Observed in differential profiles

• G1_PBS_vs_G2_DSS
• Normal_vs_Neural_Tube_Defect
• Control_vs_ZYP_High_Dose
• CIDP_patient_vs_healthy_control
• Female_Artificial_Feed_vs_Female_Grass_Feed