3α,7α,12α-Trihydroxy-24-methyl-5β-cholest-23-en-26-oic acid

Metabolite details

Identifier

OHNCMRIDBJLJKB-YWVMPULNSA-N

InChI Key

OHNCMRIDBJLJKB-YWVMPULNSA-N

IUPAC name

(E,6R)-2,3-dimethyl-6-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]hept-3-enoic acid

Preferred name

3α,7α,12α-Trihydroxy-24-methyl-5β-cholest-23-en-26-oic acid

INN name

—

Synonym

—

ChEBI

CHEBI:166746

Reactome pathways

• No Reactome pathways listed for this metabolite.

Observed in studies

• Mechanical force promotes dimethylarginine dimethylaminohydrolase 1-mediated hydrolysis of the metabolite asymmetric dimethylarginine to enhance bone formation
• Diallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice
• Mechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis
• Alterations in the gut microbiota and metabolomics of seafarers after a six-month sea voyage

Observed in differential profiles

• Control_vs_Exercise
• G1_PBS_vs_G2_DSS
• Control_vs_ZYP_High_Dose
• Control_0d_vs_Treatment_180d