7alpha-Hydroxy-3,12-dioxo-5beta-cholan-24-oic Acid

Metabolite details

Identifier

LOGQGKJLNOCUQM-RGMYPYHHSA-N

InChI Key

LOGQGKJLNOCUQM-RGMYPYHHSA-N

IUPAC name

(4R)-4-[(5R,7R,8R,9S,10S,13R,14S,17R)-7-hydroxy-10,13-dimethyl-3,12-dioxo-2,4,5,6,7,8,9,11,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid

Preferred name

7alpha-Hydroxy-3,12-dioxo-5beta-cholan-24-oic Acid

INN name

—

Synonym

—

ChEBI

CHEBI:173152

Reactome pathways

• No Reactome pathways listed for this metabolite.

Observed in studies

• Efficacy of Zhuyu Pill Intervention in a Cholestasis Rat Model: Mutual Effects on Fecal Metabolism and Microbial Diversity
• Diallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice
• Mechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis

Observed in differential profiles

• Control_vs_CF_high
• G1_PBS_vs_G2_DSS
• Control_vs_ZYP_High_Dose