alosetron

Metabolite details

Identifier

JSWZEAMFRNKZNL-UHFFFAOYSA-N

InChI Key

JSWZEAMFRNKZNL-UHFFFAOYSA-N

IUPAC name

5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one

Preferred name

alosetron

INN name

alosetron

Synonym

2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one

ChEBI

CHEBI:253342

Reactome pathways

• R-HSA-112314 - Neurotransmitter receptors and postsynaptic signal transmission
• R-HSA-112315 - Transmission across Chemical Synapses
• R-HSA-112316 - Neuronal System

Observed in studies

• Bioaccumulation of therapeutic drugs by human gut bacteria: cross-feeding metabolite analysis (FIA-MS) (E.rectale;S.salivarius assays)
• Metabolic Dynamics of In Vitro CD8+ T Cell Activation.
• Transcriptional memory of dFOXO activation in youth curtails later-life mortality
• Diallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice
• Integrated Metabolomics and Transcriptomics Analyses Reveal Anthocyanin and Carotenoid Biosynthesis Involved in Color Development in Willow Bark
• Metabolic disorder and intestinal microflora dysbiosis in chronic inflammatory demyelinating polyradiculoneuropathy
• Unraveling the metabolic effects of benzophenone-3 on the endosymbiotic dinoflagellate Cladocopium goreaui

Observed in differential profiles

• G4_Eubacterium_rectale_DMSO_30_vs_G3_Eubacterium_rectale_Duloxetine_47
• G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
• G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
• RU-_Control_vs_RU+_Switch
• G1_PBS_vs_G2_DSS
• Purple_vs_Green
• CIDP_patient_vs_healthy_control
• Control_vs_BP3_Low_Concentration