L-canavanine zwitterion

Metabolite details

Identifier

FSBIGDSBMBYOPN-VKHMYHEASA-N

InChI Key

FSBIGDSBMBYOPN-VKHMYHEASA-N

IUPAC name

(2S)-2-azaniumyl-4-(carbamimidamidooxy)butanoate

Preferred name

L-canavanine zwitterion

INN name

—

Synonym

(2S)-2-ammonio-4-(carbamimidamidooxy)butanoate

ChEBI

CHEBI:405237

Reactome pathways

• No Reactome pathways listed for this metabolite.

Observed in studies

• Bioaccumulation of therapeutic drugs by human gut bacteria: cross-feeding metabolite analysis (FIA-MS) (E.rectale;S.salivarius assays)
• Transcriptional differentiation of Trypanosoma brucei during in vitro acquisition of resistance to acoziborole
• Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors

Observed in differential profiles

• G4_Eubacterium_rectale_DMSO_30_vs_G3_Eubacterium_rectale_Duloxetine_47
• WT_vs_WT_Aco
• Wild_Type_vs_Gene_Knockout