thiamine(1+) diphosphate

Metabolite details

Identifier

AYEKOFBPNLCAJY-UHFFFAOYSA-O

InChI Key

AYEKOFBPNLCAJY-UHFFFAOYSA-O

IUPAC name

3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-[2-(diphosphooxy)ethyl]-4-methyl-1,3-thiazol-3-ium

Preferred name

thiamine(1+) diphosphate

INN name

—

Synonym

thiamine diphosphate

ChEBI

CHEBI:9532

Reactome pathways

• No Reactome pathways listed for this metabolite.

Observed in studies

• Biological effect of chronic mistranslation in mammalian cells
• Cell-based and multi-omics profiling reveal dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei
• Exercise-generated β-aminoisobutyric acid (BAIBA) reduces cardiomyocytes metabolic stress and apoptosis caused by mitochondrial dysfunction through the miR-208b/AMPK pathway
• Genetic mapping and molecular mechanism behind color variation in the Asian vine snake
• L-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS positive mode)

Observed in differential profiles

• rps2_wildtype_vs_rps2_A226Y
• Non_Induced_0_Day_vs_Induced_8_Day
• Non_Induced_0_Day_vs_Induced_8_Day
• Sham_vs_Heart_Failure_Sedentary
• Yellow_Skin_vs_Green_Skin
• SAR-S_vs_SAR-R