thiamine(1+) diphosphate(1−)

Metabolite details

Identifier

AYEKOFBPNLCAJY-UHFFFAOYSA-N

InChI Key

AYEKOFBPNLCAJY-UHFFFAOYSA-N

IUPAC name

2-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl}ethyl dihydrogen diphosphate

Preferred name

thiamine(1+) diphosphate(1−)

INN name

—

Synonym

thiamin diphosphate

ChEBI

CHEBI:45931

Reactome pathways

• No Reactome pathways listed for this metabolite.

Observed in studies

• Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Escherichia coli assays)
• Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Klebsiella pneumoniae assays)
• Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Streptococcus pneumoniae assays)
• Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Streptococcus pyogenes assays)
• F1Fo-ATP synthase subunit determines lethal pathogenic fungi infection
• PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis.
• Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency.

Observed in differential profiles

• RPMI_B36_vs_Pooled_Sera_B36
• G1_Klebsiella_pneumoniae_AJ218_RPMI_vs_G2_Klebsiella_pneumoniae_AJ218_Pooled_sera
• G1_Pooled_Sera_Blood_4559_vs_G2_RPMI_Glucose_Blood_4559
• G1_RPMI_modified_Blood_M1T1_5448_vs_G2_Pooled_sera_Blood_M1T1_5448
• WT_vs_16R
• MCF-7_WT_vs_MCF-7_PKM2_KO
• WT_vs_ErbB2_KI