F1Fo-ATP synthase subunit determines lethal pathogenic fungi infection

Study details

Source ID

https://identifiers.org/metabolights:MTBLS3332

Title

F1Fo-ATP synthase subunit determines lethal pathogenic fungi infection

Summary

F1Fo-ATP synthase δ subunit affects fungal infection.

Observation

F1Fo-ATP synthase δ subunit deletion in Candida albicans.

Findings

δ subunit deletion reduces virulence, protects against candidiasis.

Disease terms

systemic candidiasis, infection, Fungal infections, aspergillosis, candidiasis

Gene terms

—

Chemical terms

fructose 1,6-bisphosphate, ATP

Organisms

Candida albicans, C. albicans, mouse, mice

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS3332.

{
  "@type": "Dataset",
  "go_id": [
    "https://identifiers.org/GO:0005739",
    "https://identifiers.org/GO:0005737",
    "https://identifiers.org/GO:0005886",
    "https://identifiers.org/GO:0006096"
  ],
  "go_kw": [
    "mitochondrion",
    "cytoplasm",
    "plasma membrane",
    "glycolysis"
  ],
  "integmet_study": "MTBLS3332",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:C029063",
    "https://identifiers.org/mesh:D000255"
  ],
  "mesh_chemical_pubtator_kw": [
    "fructose 1,6-bisphosphate",
    "ATP"
  ],
  "mesh_disease_id": [
    "https://identifiers.org/mesh:C536777",
    "https://identifiers.org/mesh:D007239",
    "https://identifiers.org/mesh:D009181",
    "https://identifiers.org/mesh:D001228",
    "https://identifiers.org/mesh:D002177"
  ],
  "mesh_disease_pubtator_kw": [
    "systemic candidiasis",
    "infection",
    "Fungal infections",
    "aspergillosis",
    "candidiasis"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:5476",
    "https://identifiers.org/taxonomy:10090"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "Candida albicans",
    "C. albicans",
    "mouse",
    "mice"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS3332",
  "study_findings": "\u03b4 subunit deletion reduces virulence, protects against candidiasis.",
  "study_observation": "F1Fo-ATP synthase \u03b4 subunit deletion in Candida albicans.",
  "study_summary": "F1Fo-ATP synthase \u03b4 subunit affects fungal infection.",
  "study_title_original": "F1Fo-ATP synthase  subunit determines lethal pathogenic fungi infection"
}