almotriptan

Metabolite details

Identifier

WKEMJKQOLOHJLZ-UHFFFAOYSA-N

InChI Key

WKEMJKQOLOHJLZ-UHFFFAOYSA-N

IUPAC name

N,N-dimethyl-2-{5-[(pyrrolidin-1-ylsulfonyl)methyl]-1H-indol-3-yl}ethanamine

Preferred name

almotriptan

INN name

almotriptan

Synonym

1-(((3-(2-(Dimethylamino)ethyl)indol-5-yl)methyl)sulfonyl)pyrrolidine

ChEBI

CHEBI:520985

Reactome pathways

• No Reactome pathways listed for this metabolite.

Observed in studies

• Bioaccumulation of therapeutic drugs by human gut bacteria: cross-feeding metabolite analysis (FIA-MS) (E.rectale;S.salivarius assays)
• Diallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice
• DT-109 ameliorates nonalcoholic steatohepatitis in nonhuman primates

Observed in differential profiles

• G4_Eubacterium_rectale_DMSO_30_vs_G3_Eubacterium_rectale_Duloxetine_47
• G1_PBS_vs_G2_DSS
• Control_Liver_vs_Treatment_Liver