3-hydroxykynurenine

Metabolite details

Identifier

VCKPUUFAIGNJHC-UHFFFAOYSA-N

InChI Key

VCKPUUFAIGNJHC-UHFFFAOYSA-N

IUPAC name

3-(2-amino-3-hydroxybenzoyl)alanine

Preferred name

3-hydroxykynurenine

INN name

—

Synonym

2-amino-4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid

ChEBI

CHEBI:1547

Reactome pathways

• No Reactome pathways listed for this metabolite.

Observed in studies

• Metabolic Dynamics of In Vitro CD8+ T Cell Activation.
• Metabolic Responses of a Model Green Microalga Euglena gracilis to Different Environmental Stresses
• Distinct succinate modifying products are clinically diagnostic and prognostic biomarkers for fumarate hydratase deficient renal cell carcinoma
• Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors

Observed in differential profiles

• G3_Experimental_Sample_0h_vs_G11_Experimental_Sample_96h
• Control_vs_Paramycin
• Normal_control_no_tumor_vs_FH_deficient_RCC
• Wild_Type_vs_Gene_Knockout