4-hydroxy-L-glutamate(1−)

Metabolite details

Identifier

HBDWQSHEVMSFGY-SCQFTWEKSA-M

InChI Key

HBDWQSHEVMSFGY-SCQFTWEKSA-M

IUPAC name

hydrogen 4-hydroxy-L-glutamate

Preferred name

4-hydroxy-L-glutamate(1−)

INN name

—

Synonym

(2S)-2-ammonio-4-hydroxypentanedioate

ChEBI

CHEBI:32812

Reactome pathways

• No Reactome pathways listed for this metabolite.

Observed in studies

• PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis.
• Integrated Proteomic and Metabolomic Analyses Show Differential Effects of Glucose Availability in Marine <i>Synechococcus</i> and <i>Prochlorococcus</i>.
• Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency.

Observed in differential profiles

• MCF-7_WT_vs_MCF-7_PKM2_KO
• SS120_Control_vs_SS120_5mM
• SS120_Control_vs_SS120_5mM
• SS120_Control_vs_SS120_5mM
• SS120_Control_vs_SS120_5mM
• SS120_Control_vs_SS120_5mM
• WT_vs_ErbB2_KI