glimepiride

Metabolite details

Identifier

WIGIZIANZCJQQY-RUCARUNLSA-N

InChI Key

WIGIZIANZCJQQY-RUCARUNLSA-N

IUPAC name

3-ethyl-4-methyl-N-[2-(4-{[(trans-4-methylcyclohexyl)carbamoyl]sulfamoyl}phenyl)ethyl]-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide

Preferred name

glimepiride

INN name

glimépiride

Synonym

1-{[4-(2-{[(3-ethyl-4-methyl-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)carbonyl]amino}ethyl)phenyl]sulfonyl}-3-(trans-4-methylcyclohexyl)urea

ChEBI

CHEBI:5383

Reactome pathways

• R-HSA-1430728 - Metabolism
• R-HSA-163685 - Integration of energy metabolism
• R-HSA-422356 - Regulation of insulin secretion

Observed in studies

• Diallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice
• Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Feces metabolomics)
• Transcriptomic and lipidomic profiling of subcutaneous and visceral adipose tissues in 15 vertebrates

Observed in differential profiles

• G1_PBS_vs_G2_DSS
• Normal_vs_Neural_Tube_Defect
• G1_Sheep_ASA_SAT_vs_G2_Sheep_GOM_VAT