saxagliptin

Metabolite details

Identifier

QGJUIPDUBHWZPV-SGTAVMJGSA-N

InChI Key

QGJUIPDUBHWZPV-SGTAVMJGSA-N

IUPAC name

(1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile

Preferred name

saxagliptin

INN name

saxagliptin

Synonym

(1S,3S,5S)-2-((2S)-Amino(3-hydroxytricyclo(3.3.1.13,7)dec-1-yl)acetyl)-2-azabicyclo(3.1.0)hexane-3-carbonitrile

ChEBI

CHEBI:71272

Reactome pathways

• R-HSA-2980736 - Peptide hormone metabolism
• R-HSA-381771 - Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
• R-HSA-392499 - Metabolism of proteins
• R-HSA-400508 - Incretin synthesis, secretion, and inactivation

Observed in studies

• Multi-Omics Analysis Reveals Disturbance of Nanosecond Pulsed Electric Field in the Serum Metabolic Spectrum and Gut Microbiota
• Intergenerational Association of Gut Microbiota and Metabolism between Perinatal Folic Acid Metabolism and Neural Tube Defects (Feces metabolomics)
• Mechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis
• Transcriptomic and lipidomic profiling of subcutaneous and visceral adipose tissues in 15 vertebrates

Observed in differential profiles

• Control_vs_nsPEF_7_day
• Normal_vs_Neural_Tube_Defect
• Control_vs_ZYP_High_Dose
• G1_Sheep_ASA_SAT_vs_G2_Sheep_GOM_VAT