12(S)-HEPE

Metabolite details

Identifier

MCRJLMXYVFDXLS-UOLHMMFFSA-N

InChI Key

MCRJLMXYVFDXLS-UOLHMMFFSA-N

IUPAC name

(5Z,8Z,10E,12S,14Z,17Z)-12-hydroxyicosa-5,8,10,14,17-pentaenoic acid

Preferred name

12(S)-HEPE

INN name

—

Synonym

12S-hydroxy-5Z,8Z,10E,14Z,17Z-eicosapentaenoic acid

ChEBI

CHEBI:88345

Reactome pathways

• No Reactome pathways listed for this metabolite.

Observed in studies

• Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the developing brain
• Collagen induced arthritis in dba/1j mice associates with oxylipin changes in plasma
• Metabolism Disorder Promotes Isoproterenol-induced Myocardial Injury in Mice with High Temperature and High Humidity and High-Fat Diet

Observed in differential profiles

• n-3_PUFA_sufficient_vs_n-3_PUFA_deficient
• Control_vs_CIA
• Control_vs_Isoproterenol