Collagen induced arthritis in dba/1j mice associates with oxylipin changes in plasma

Study details

Source ID

https://identifiers.org/metabolights:MTBLS243

Title

Collagen induced arthritis in dba/1j mice associates with oxylipin changes in plasma

Summary

Oxylipin changes in CIA and control mice.

Observation

Differences in oxylipin levels between CIA and control mice.

Findings

10 oxylipins dysregulated in CIA mice; associated with inflammation and apoptosis dysregulation.

Disease terms

CIA, Arthritis, inflammation, arthritis, RA, rheumatoid arthritis

Gene terms

NF-kappaB, PPAR-gamma

Chemical terms

lipopolysaccharide, Oxylipin, LPS, oxylipin, Oxylipins, oxylipins

Organisms

mice, Mice

Raw data (JSON) Show

Also available at /api/study/https://identifiers.org/metabolights:MTBLS243.

{
  "@type": "Dataset",
  "go_id": [
    "https://identifiers.org/GO:0006954",
    "https://identifiers.org/GO:0006915"
  ],
  "go_kw": [
    "inflammation",
    "apoptosis"
  ],
  "integmet_study": "MTBLS243",
  "mesh_chemical_id": [
    "https://identifiers.org/mesh:D008070",
    "https://identifiers.org/mesh:D054883"
  ],
  "mesh_chemical_pubtator_kw": [
    "lipopolysaccharide",
    "Oxylipin",
    "LPS",
    "oxylipin",
    "Oxylipins",
    "oxylipins"
  ],
  "mesh_disease_id": [
    "https://identifiers.org/mesh:D001169",
    "https://identifiers.org/mesh:D001168",
    "https://identifiers.org/mesh:D007249",
    "https://identifiers.org/mesh:D001172"
  ],
  "mesh_disease_pubtator_kw": [
    "CIA",
    "Arthritis",
    "inflammation",
    "arthritis",
    "RA",
    "rheumatoid arthritis"
  ],
  "mesh_gene_id": [
    "https://identifiers.org/ncbigene:18033",
    "https://identifiers.org/ncbigene:19016"
  ],
  "mesh_gene_pubtator_kw": [
    "NF-kappaB",
    "PPAR-gamma"
  ],
  "ncbi_taxonomy_id": [
    "https://identifiers.org/taxonomy:10090"
  ],
  "ncbi_taxonomy_pubtator_kw": [
    "mice",
    "Mice"
  ],
  "source_id": "https://identifiers.org/metabolights:MTBLS243",
  "study_findings": "10 oxylipins dysregulated in CIA mice; associated with inflammation and apoptosis dysregulation.",
  "study_observation": "Differences in oxylipin levels between CIA and control mice.",
  "study_summary": "Oxylipin changes in CIA and control mice.",
  "study_title_original": "Collagen induced arthritis in dba/1j mice associates with oxylipin changes in plasma"
}