5-HEPE

Metabolite details

Identifier

FTAGQROYQYQRHF-FCWZHQICSA-N

InChI Key

FTAGQROYQYQRHF-FCWZHQICSA-N

IUPAC name

(6E,8Z,11Z,14Z,17Z)-5-hydroxyicosa-6,8,11,14,17-pentaenoic acid

Preferred name

5-HEPE

INN name

—

Synonym

(±)-5-hydroxy-6E,8Z,11Z,14Z,17Z-eicosapentaenoic acid

ChEBI

CHEBI:72801

Reactome pathways

• No Reactome pathways listed for this metabolite.

Observed in studies

• Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the developing brain
• Lipid mediators of inflammation in BALF 6-19 days after infection with influenza.
• Lipid mediators of inflammation in BALF 3-11 days after infection with influenza.
• Mechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis

Observed in differential profiles

• n-3_PUFA_sufficient_vs_n-3_PUFA_deficient
• Mock_19d_vs_PR8_19d
• G1_Mock_11_day_vs_G5_PR8_11_day
• G1_Mock_11_day_vs_G5_PR8_11_day
• Control_vs_ZYP_High_Dose