crenolanib — integMET

Metabolite details

Identifier: DYNHJHQFHQTFTP-UHFFFAOYSA-N
InChI Key: DYNHJHQFHQTFTP-UHFFFAOYSA-N
IUPAC name: 1-(2-{5-[(3-methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine
Preferred name: crenolanib
INN name: crenolanibum
Synonym: 1-(2-{5-[(3-methyloxetan-3-yl)methoxy]-1H-1,3-benzodiazol-1-yl}quinolin-8-yl)piperidin-4-amine
ChEBI: CHEBI:145365

R-HSA-1280215 - Cytokine Signaling in Immune system
R-HSA-162582 - Signal Transduction
R-HSA-1643685 - Disease
R-HSA-168256 - Immune System
R-HSA-186797 - Signaling by PDGF
R-HSA-5663202 - Diseases of signal transduction by growth factor receptors and second messengers
R-HSA-9006934 - Signaling by Receptor Tyrosine Kinases
R-HSA-9607240 - FLT3 Signaling
R-HSA-9671555 - Signaling by PDGFR in disease
R-HSA-9674428 - PDGFR mutants bind TKIs
R-HSA-9682385 - FLT3 signaling in disease
R-HSA-9702506 - Drug resistance of FLT3 mutants
R-HSA-9702509 - FLT3 mutants bind TKIs
R-HSA-9702581 - crenolanib-resistant FLT3 mutants