{"chebi_id":"145365","chebi_name":"crenolanib","chebi_synonyms":["1-(2-{5-[(3-methyloxetan-3-yl)methoxy]-1H-1,3-benzodiazol-1-yl}quinolin-8-yl)piperidin-4-amine","CP868569","1-[2-[5-[(3-methyl-3-oxetanyl)methoxy]-1-benzimidazolyl]-8-quinolyl]-4-piperidinamine","1-(2-(5-((3-methyloxetan-3-yl)methoxy)-1H-benzo-[d]imidazol-1-yl)quinolin-8-yl)piperidin-4-amine","1-[2-[5-[(3-methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl]-8-quinolinyl]-4-piperidinamine","1-(2-{5-[(3-methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine","crenolanibum","cr\u00e9nolanib","ARO-002","ARO 002","CP-868596","CP 868596","CP-868,596"],"diffprof_id_observed":["MTBLS2871_0001_00000009"],"diffprof_id_var_observed":[],"inchikey":"DYNHJHQFHQTFTP-UHFFFAOYSA-N","inn_name":"crenolanibum","iupac_name":"1-(2-{5-[(3-methyloxetan-3-yl)methoxy]-1<em>H</em>-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine","num_study_observed":1,"reactome_ids":["R-HSA-1280215","R-HSA-162582","R-HSA-1643685","R-HSA-168256","R-HSA-186797","R-HSA-5663202","R-HSA-9006934","R-HSA-9607240","R-HSA-9671555","R-HSA-9674428","R-HSA-9682385","R-HSA-9702506","R-HSA-9702509","R-HSA-9702581"],"reactome_names":["Cytokine Signaling in Immune system","Signal Transduction","Disease","Immune System","Signaling by PDGF","Diseases of signal transduction by growth factor receptors and second messengers","Signaling by Receptor Tyrosine Kinases","FLT3 Signaling","Signaling by PDGFR in disease","PDGFR mutants bind TKIs","FLT3 signaling in disease","Drug resistance of FLT3 mutants","FLT3 mutants bind TKIs","crenolanib-resistant FLT3 mutants"],"study_id_observed":["MTBLS2871"],"study_id_var_observed":[],"synonym_name":"1-(2-{5-[(3-methyloxetan-3-yl)methoxy]-1<em>H</em>-1,3-benzodiazol-1-yl}quinolin-8-yl)piperidin-4-amine"}