erlotinib

Metabolite details

Identifier

AAKJLRGGTJKAMG-UHFFFAOYSA-N

InChI Key

AAKJLRGGTJKAMG-UHFFFAOYSA-N

IUPAC name

N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine

Preferred name

erlotinib

INN name

erlotinibum

Synonym

[6,7-bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine

ChEBI

CHEBI:114785

Reactome pathways

• R-HSA-1236382 - Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
• R-HSA-1643685 - Disease
• R-HSA-1643713 - Signaling by EGFR in Cancer
• R-HSA-5637815 - Signaling by Ligand-Responsive EGFR Variants in Cancer
• R-HSA-5663202 - Diseases of signal transduction by growth factor receptors and second messengers

Observed in studies

• Metabolomic Insights into the Browning of the Peel of Bagging ‘Rui Xue’ Apple Fruit
• Multi-Omics Analysis Reveals Disturbance of Nanosecond Pulsed Electric Field in the Serum Metabolic Spectrum and Gut Microbiota
• Diallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice

Observed in differential profiles

• Non_Bagged_Fruits_vs_Bagged_Fruits_With_Browning
• Control_vs_nsPEF_7_day
• G1_PBS_vs_G2_DSS