Wild_Type_vs_TMAVA_Treatment

Profile details

Identifier: MTBLS3174_0004_00000002
Linked study: MTBLS3174 — Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy
Comparison: Wild_Type vs TMAVA_Treatment
Group A: Wild type mice with no treatment or knockout.. Serves as the reference group for evaluating the effects of TMAVA treatment and BBOX knockout.
Group B: Wild type mice treated with TMAVA.. Crucial for evaluating the pathophysiological effects of TMAVA on cardiac hypertrophy.
Total features tested: 62
Significant features: 47
p-value threshold: 0.05
Ratio threshold (upper): 1.5
Ratio threshold (lower): 1/1.5
Date created: 2025-09-26 00:00:00

Metabolite ID (InChI Key)	Name	Direction	Ratio	p-value
FAUYAENFVCNTAL-PFFNLMTBSA-N	GPC(18:0/22:6)	up	9.668	1.29e-11
KSRURLYJRNYEOH-SHHFQLSYSA-N	1-heptadecanoyl-2-((4<i>Z</i>,7<i>Z</i>,10<i>Z</i>,13<i>Z</i>,16<i>Z</i>,19<i>Z</i>)-docosahexaenoyl)-<em>sn</em>-glycero-3-phosphocholine	up	13.63	2.06e-08
HRPRHMPJUIFSCB-KYPHJRDXSA-N	[(2R)-3-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoyl]oxy-2-nonadecanoyloxypropyl] 2-(trimethylazaniumyl)ethyl phosphate	up	22.1	1.33e-06
APEHGLQXFOZAEF-MHNOHXJZSA-N	—	up	5.871	3.54e-08
SBYLHTNKEWSLBA-CPRJDYHCSA-N	—	up	3.078	2.97e-11
RFVFQQWKPSOBED-PSXMRANNSA-N	1-tetradecanoyl-2-hexadecanoyl-<em>sn</em>-glycero-3-phosphocholine	up	4.291	2.41e-08
LSOWKZULVQWMLY-APPDJCNMSA-N	Lyso(22:6(4<i>Z</i>,7<i>Z</i>,10<i>Z</i>,13<i>Z</i>,16<i>Z</i>,19<i>Z</i>)/0:0)	up	16.76	0.00138
SGQIECCWAOPTNL-LEFPGAKQSA-N	[(2R)-1-[2-aminoethoxy(hydroxy)phosphoryl]oxy-3-[(11Z,14Z)-icosa-11,14-dienoyl]oxypropan-2-yl] (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoate	up	3.911	1.42e-06
WAFWSBFKIPCFOF-ZDAJSWCOSA-N	PC(20:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))	up	4.126	5.46e-06
KILNVBDSWZSGLL-KXQOOQHDSA-N	GPC(16:0/16:0)	up	3.114	2.86e-07