{"@type":"Dataset","go_id":["https://identifiers.org/GO:0019395","https://identifiers.org/GO:0009437","https://identifiers.org/GO:0046322"],"go_kw":["fatty acid oxidation (FAO)","carnitine metabolism","inhibition of fatty acid oxidation (FAO)"],"integmet_study":"MTBLS3174","mesh_chemical_id":["https://identifiers.org/mesh:D002331","https://identifiers.org/mesh:D008055","https://identifiers.org/mesh:C000713634","https://identifiers.org/mesh:D005227","https://identifiers.org/mesh:C003712"],"mesh_chemical_pubtator_kw":["carnitine","lipid","TMAVA","N,N,N-trimethyl-5-aminovaleric acid","fatty acid","trimethyllysine"],"mesh_disease_id":["https://identifiers.org/mesh:D006331","https://identifiers.org/mesh:D006333","https://identifiers.org/mesh:D006332"],"mesh_disease_pubtator_kw":["diseased heart","heart failure","cardiac hypertrophy","cardiac hypertrophy and dysfunction","contractile dysfunction"],"mesh_gene_id":["https://identifiers.org/ncbigene:170442"],"mesh_gene_pubtator_kw":["gamma-butyrobetaine hydroxylase"],"ncbi_taxonomy_id":["https://identifiers.org/taxonomy:10090"],"ncbi_taxonomy_pubtator_kw":["mice","Mice"],"source_id":"https://identifiers.org/metabolights:MTBLS3174","study_findings":"TMAVA inhibits carnitine synthesis, reducing FAO and accelerating cardiac hypertrophy.","study_observation":"Gut microbiota production of TMAVA and its effects on cardiac hypertrophy.","study_summary":"TMAVA affects cardiac hypertrophy via carnitine inhibition.","study_title_original":"Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy"}