Diff Profiles › MTBLS3174_0003_00000002

Wild_Type_vs_TMAVA_Treatment

Wild_Type vs TMAVA_Treatment

p-value ≤ 0.05 7 significant 2025-09-26 00:00:00 Study: MTBLS3174
11 Total Features
7 Significant
0.05 p-value Threshold

Profile details

Identifier
MTBLS3174_0003_00000002
Linked study
MTBLS3174 — Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy
Comparison
Wild_Type vs TMAVA_Treatment
Group A
Wild type mice with no treatment or knockout.. Serves as the reference group for evaluating the effects of TMAVA treatment and BBOX knockout.
Group B
Wild type mice treated with TMAVA.. Crucial for evaluating the pathophysiological effects of TMAVA on cardiac hypertrophy.
Total features tested
11
Significant features
7
p-value threshold
0.05
Ratio threshold (upper)
1.5
Ratio threshold (lower)
1/1.5
Date created
2025-09-26 00:00:00

Top hits

Metabolite ID (InChI Key) Name Direction Ratio p-value
IESVDEZGAHUQJU-ZLBXKVHBSA-N Phosphatidylcholine(16:0/22:6ω3) up 14.08 1.06e-08
SVRBKLJIDJHADS-USWSLJGRSA-N LPE(18:2) down 0.1491 4.47e-05
SPJFYYJXNPEZDW-FTJOPAKQSA-N 1-Linoleoylglycerophosphocholine down 0.2618 2.52e-05
TWBVHOYVCUOMJY-PAUXXPOVSA-N LPE 0:0/22:6(4<i>Z</i>,7<i>Z</i>,10<i>Z</i>,13<i>Z</i>,16<i>Z</i>,19<i>Z</i>) up 3.108 2.06e-05
LAXQYRRMGGEGOH-JXRLJXCWSA-N PC(20:4(5<i>Z</i>,8<i>Z</i>,11<i>Z</i>,14<i>Z</i>)/0:0) up 2.664 3.76e-05
YWOCITMXHHTBAW-XSQXPFHXSA-N Lyso-PE(0:0/20:4(5<i>Z</i>,8<i>Z</i>,11<i>Z</i>,14<i>Z</i>)) down 0.5 0.000141
CZYOFWNORPEFDG-KOIKXXGWSA-N LysoPE(0:0/18:1(11Z)) down 0.5769 8.67e-05